Structural Classification of Proteins
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Superfamily: Formate/glycerate dehydrogenase catalytic domain-like

link to SUPERFAMILY database - Superfamily

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: Flavodoxin-like [52171]
    3 layers, a/b/a; parallel beta-sheet of 5 strand, order 21345
  4. Superfamily: Formate/glycerate dehydrogenase catalytic domain-like [52283]
    link to SUPERFAMILY database - Superfamily

Families:

  1. Formate/glycerate dehydrogenases, substrate-binding domain [52284] (9)
    this domain is interrupted by the Rossmann-fold domain
    1. Formate dehydrogenase [52285]
      contains an additional beta-hairpin after the common fold
      1. Pseudomonas sp., strain 101 [TaxId: 306] [52286] (2) picpic
    2. Putative formate dehydrogenase [52287]
      1. Archaeon Pyrobaculum aerophilum [TaxId: 13773] [52288] (1) picpic
    3. Transcription corepressor CtbP [82347]
      C-terminal binding protein 1; a dehydrogenase
      1. Human (Homo sapiens), Ctbp1 [TaxId: 9606] [82348] (1) picpic
      2. Rat (Rattus norvegicus), Ctbp3 [TaxId: 10116] [89597] (2) picpic
    4. D-2-hydroxyisocaproate dehydrogenase [52289]
      1. Lactobacillus casei [TaxId: 1582] [52290] (1) picpic
    5. D-glycerate dehydrogenase [52291]
      1. Hyphomicrobium methylovorum [TaxId: 84] [52292] (1) picpic
    6. Phosphoglycerate dehydrogenase [52293]
      has additional C-terminal domain of the ferredoxin fold
      1. Escherichia coli [TaxId: 562] [52294] (18) picpic
      2. Mycobacterium tuberculosis [TaxId: 1773] [142063] (2) picpic
        SQ P0A544 2-97,282-315
        there is an intervening domain between this domain and regulatory (C-terminal) domain
    7. D-lactate dehydrogenase [52295]
      1. Lactobacillus helveticus [TaxId: 1587] [52296] (3) picpic
  2. L-alanine dehydrogenase-like [52297] (2)
    1. L-alanine dehydrogenase [52298]
      1. Phormidium lapideum [TaxId: 32060] [52299] (3) picpic
    2. Nicotinamide nucleotide transhydrogenase dI component [63963]
      L-alanine dehydrogenase homologue
      1. Rhodospirillum rubrum [TaxId: 1085] [63964] (28) picpic
  3. S-adenosylhomocystein hydrolase [52300] (3)
    1. S-adenosylhomocystein hydrolase [52301]
      contains additional secondary structures disguising the superfamily fold
      1. Human (Homo sapiens) [TaxId: 9606] [52302] (2) picpic
      2. Rat (Rattus norvegicus) [TaxId: 10116] [52303] (17) picpic
      3. Plasmodium falciparum, isolate 3D7 [TaxId: 5833] [117480] (1) picpic
        SQ P50250
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk