Structural Classification of Proteins

Superfamily: CheY-like

: uperfamily

Lineage:

Root: scop
Class: Alpha and beta proteins (a/b) [51349]
Mainly parallel beta sheets (beta-alpha-beta units)
Fold: Flavodoxin-like [52171]
3 layers, a/b/a; parallel beta-sheet of 5 strand, order 21345
Superfamily: CheY-like [52172]
uperfamily

Families:

CheY-related [52173] (32)
1. CheY protein [52174]
  1. Escherichia coli [TaxId: 562] [52175] (35)
    SQ P06143
    1. 1jbe
      meta-active conformation
      complexed with acy, gol, snn, so4
      1. chain a [62845]
    2. 3chy
      complexed with so4
      1. chain a [31038]
    3. 1u8t
      complexed with so4; mutant
      1. chain a [113192]
      2. chain b [113193]
      3. chain c [113194]
      4. chain d [113195]
    4. 1chn
      complexed with mg
      1. chain a [31040]
    5. 1e6m
      mutant
      1. chain a [31039]
    6. 1ymv
      complexed with mg; mutant
      1. chain a [31045]
    7. 1udr
      mutant
      1. chain a [31041]
      2. chain b [31042]
      3. chain c [31043]
      4. chain d [31044]
    8. 1d4z
      complexed with so4; mutant
      1. chain a [31047]
    9. 1e6l
      mutant
      1. chain a [59307]
    10. 1vlz
      mutant
      1. chain a [31048]
      2. chain b [31049]
    11. 1c4w
      thiophosphonate modified
      mutant
      1. chain a [31046]
    12. 1ffg
      complexed with mn
      1. chain a [31051]
      2. chain c [31052]
    13. 1e6k
      mutant
      1. chain a [59306]
    14. 5chy
      complexed with ca; mutant
      1. chain a [31050]
    15. 1f4v
      bound to the N-terminus of FliM
      complexed with bef, gol, mg
      1. chain a [31058]
      2. chain b [31059]
      3. chain c [31060]
    16. 1ab6
      mutant
      1. chain a [31054]
      2. chain b [31055]
    17. 2b1j
      automatically matched to 1ZDM A:2-129
      complexed with mg
      1. region a:2-129 [127670]
    18. 2b1j
      automatically matched to 1ZDM A:2-129
      complexed with mg
      1. region b:2-129 [127671]
    19. 1ab5
      mutant
      1. chain a [31056]
      2. chain b [31057]
    20. 1fqw
      complexed with bef, mn
      1. chain a [59992]
      2. chain b [59993]
    21. 1zdm
      complexed with bfd, mn, xe
      1. region a:2-129 [124941]
    22. 1zdm
      automatically matched to 1ZDM A:2-129
      complexed with bfd, mn, xe
      1. region b:2-129 [124942]
    23. 1hey
      mutant
      1. chain a [31061]
    24. 1ffs
      complexed with mn
      1. chain a [31068]
      2. chain c [31069]
    25. 6chy
      complexed with so4; mutant
      1. chain a [31062]
      2. chain b [31063]
    26. 1ymu
      mutant
      1. chain a [31066]
      2. chain b [31067]
    27. 1eay
      1. chain a [31064]
      2. chain b [31065]
    28. 1bdj
      complexed with so4
      1. chain a [31070]
    29. 1mih
      complexed with bef, mn, so4; mutant
      1. chain a [84975]
      2. chain b [84976]
    30. 1ffw
      complexed with mn, pon
      1. chain a [31075]
      2. chain c [31076]
    31. 1a0o
      complexed with mn
      1. chain a [31071]
      2. chain c [31072]
      3. chain e [31073]
      4. chain g [31074]
    32. 1kmi
      complexed with CheZ
      complexed with bcn, bef, mg; mutant
      1. chain y [72751]
    33. 1cye
      mutant
      1. chain a [31077]
    34. 1djm
      BeF3-activated
      1. chain a [31078]
    35. 1ehc
      naturally-occurring mutant
      1. chain a [31053]
  2. Salmonella typhimurium [TaxId: 90371] [52176] (18)
    1. 2fka
      automatically matched to d2che__
      complexed with bef, cxs, mg, so4
      1. region a:2-129 [133649]
    2. 2flw
      automatically matched to d2che__
      complexed with bef, mg, so4
      1. region a:2-129 [133751]
    3. 2fmf
      automatically matched to d2che__
      complexed with so4
      1. region a:2-129 [133773]
    4. 2flk
      automatically matched to d2che__
      complexed with cxs, so4
      1. region a:2-129 [133726]
    5. 2fmk
      automatically matched to d2che__
      complexed with ace, bef, mg
      1. region a:2-129 [133777]
    6. 2chf
      1. chain a [31079]
    7. 2fmh
      automatically matched to d2che__
      complexed with bef, gol, mg, so4, trs
      1. region a:2-129 [133775]
    8. 2fmi
      automatically matched to d2che__
      complexed with gol, so4, trs
      1. region a:2-129 [133776]
    9. 2che
      complexed with mg
      1. chain a [31080]
    10. 2pl9
      automatically matched to d2chea_
      complexed with bef, mes, mg
      1. region a:2-129 [149622]
    11. 2pl9
      automatically matched to d2chea_
      complexed with bef, mes, mg
      1. region b:2-129 [149623]
    12. 2pl9
      automatically matched to d2chea_
      complexed with bef, mes, mg
      1. region c:2-129 [149624]
    13. 2pmc
      automatically matched to d2chea_
      complexed with mg
      1. region a:2-129 [149659]
    14. 2pmc
      automatically matched to d2chea_
      complexed with mg
      1. region b:2-129 [149660]
    15. 2pmc
      automatically matched to d2chea_
      complexed with mg
      1. region c:2-129 [149661]
    16. 2pmc
      automatically matched to d2chea_
      complexed with mg
      1. region d:2-129 [149662]
    17. 1cey
      1. chain a [31082]
    18. 2chy
      CA-atoms only, mutant protein sequence
      1. chain a [31081]
  3. Thermotoga maritima [TaxId: 2336] [52177] (5)
    SQ Q56312
    1. 1u0s
      1. chain y [107566]
    2. 1tmy
      1. chain a [31083]
    3. 3tmy
      complexed with mn
      1. chain a [31084]
      2. chain b [31085]
    4. 2tmy
      1. chain a [31086]
    5. 4tmy
      complexed with mg
      1. chain a [31087]
      2. chain b [31088]
  4. Sinorhizobium meliloti, CheY2 [TaxId: 382] [102225] (2)
    SQ Q52884
    1. 1p6q
      1. chain a [104074]
    2. 1p6u
      1. chain a [94190]
2. Nitrate/nitrite response regulator (NarL), receiver domain [52178]
  1. Escherichia coli [TaxId: 562] [52179] (2)
    1. 1a04
      1. region a:5-142 [31089]
      2. region b:5-142 [31090]
    2. 1rnl
      complexed with gol, pt
      1. region a:5-142 [31091]
3. NTRC receiver domain [52180]
  1. Salmonella typhimurium [TaxId: 90371] [52181] (6)
    1. 1krw
      1. chain a [91024]
    2. 1krx
      complexed with bef
      1. chain a [91025]
    3. 1j56
      complexed with bef
      1. chain a [90881]
    4. 1ntr
      1. chain a [31092]
    5. 1dc7
      1. chain a [31093]
    6. 1dc8
      1. chain a [31094]
4. Transcriptional regulatory protein FixJ, receiver domain [52182]
  1. Rhizobium meliloti [TaxId: 382] [52183] (4)
    1. 1dbw
      1. chain a [31095]
      2. chain b [31096]
    2. 1dck
      1. chain a [31097]
      2. chain b [31098]
    3. 1d5w
      phosphorylated form
      complexed with pas, so4; mutant
      1. chain a [31099]
      2. chain b [31100]
      3. chain c [31101]
    4. 1dcm
      complexed with mg; mutant
      1. chain a [31102]
      2. chain b [31103]
5. Transcriptional regulatory protein DctD, receiver domain [52184]
  1. Sinorhizobium meliloti [TaxId: 382] [52185] (3)
    1. 1qkk
      also includes a part of the linker region
      1. chain a [31104]
    2. 1l5y
      also includes a part of the linker region
      complexed with bef, bf2, bf4, cry, mg, so4; mutant
      1. chain a [77720]
      2. chain b [77721]
    3. 1l5z
      also includes a part of the linker region
      complexed with cry, so4; mutant
      1. chain a [77722]
6. Sporulation response regulator Spo0A [52186]
  1. Bacillus stearothermophilus [TaxId: 1422] [52187] (2)
    1. 1dz3
      C-terminal helix-swapping dimer
      complexed with so4
      1. chain a [31105]
    2. 1qmp
      1. chain a [31106]
      2. chain b [31107]
      3. chain c [31108]
      4. chain d [31109]
7. Sporulation response regulator Spo0F [52188]
  1. Bacillus subtilis [TaxId: 1423] [52189] (11)
    SQ P06628
    1. 1pey
      complexed with mn; mutant
      1. chain a [104137]
      2. chain b [104138]
      3. chain c [104139]
    2. 1nat
      1. chain a [31113]
    3. 2ftk
      automatically matched to d1srrc_
      complexed with bfd, mg; mutant
      1. region e:1203-1321 [134069]
    4. 2ftk
      automatically matched to d1srrc_
      complexed with bfd, mg; mutant
      1. region f:1003-1121 [134070]
    5. 2ftk
      automatically matched to d1srrc_
      complexed with bfd, mg; mutant
      1. region g:1603-1721 [134071]
    6. 2ftk
      automatically matched to d1srrc_
      complexed with bfd, mg; mutant
      1. region h:1403-1521 [134072]
    7. 1f51
      complexed with mg
      1. chain e [31114]
      2. chain f [31115]
      3. chain g [31116]
      4. chain h [31117]
    8. 1fsp
      1. chain a [31118]
    9. 2fsp
      1. chain a [31119]
    10. 1pux
      1. chain a [95140]
    11. 1srr
      phosphatase resistant mutant
      1. chain a [31110]
      2. chain b [31111]
      3. chain c [31112]
8. Methylesterase CheB, N-terminal domain [52190]
  1. Salmonella typhimurium [TaxId: 90371] [52191] (1)
    1. 1a2o
      1. region a:1-140 [31120]
      2. region b:1-140 [31121]
9. PhoB receiver domain [52192]
  1. Thermotoga maritima [TaxId: 2336] [69445] (1)
    1. 1kgs
      complexed with scn
      1. region a:2-123 [68597]
  2. Escherichia coli [TaxId: 562] [52193] (7)
    1. 1zes
      automatically matched to d1b00a_
      complexed with bef, mg; mutant
      1. region a:3-123 [124994]
    2. 1zes
      automatically matched to d1b00a_
      complexed with bef, mg; mutant
      1. region b:3-122 [124995]
    3. 1zes
      automatically matched to d1b00a_
      complexed with bef, mg; mutant
      1. region c:3-122 [124996]
    4. 1b00
      1. chain a [31122]
      2. chain b [31123]
    5. 2iyn
      automatically matched to d1b00a_
      complexed with mg
      1. region a:3-121 [137803]
    6. 2iyn
      automatically matched to d1b00a_
      complexed with mg
      1. region b:3-121 [137804]
    7. 2iyn
      automatically matched to d1b00a_
      complexed with mg
      1. region c:3-121 [137805]
10. PhoP receiver domain [82340]
  1. Bacillus subtilis [TaxId: 1423] [82341] (1)
    1. 1mvo
      complexed with mn, na
      1. chain a [79513]
  2. Escherichia coli [TaxId: 562] [159479] (3)
    SQ P23836 1-119
    1. 2pl1
      automatically matched to 2PKX A:1-119
      complexed with bef, mg, pt; mutant
      1. region a:1-119 [149610]
    2. 2pkx
      mutant
      1. region a:1-119 [149606]
    3. 2pkx
      automatically matched to 2PKX A:1-119
      mutant
      1. region b:1-119 [149607]
11. Response regulator DrrB [89587]
  1. Thermotoga maritima [TaxId: 2336] [89588] (1)
    1. 1p2f
      complexed with mse
      1. region a:1-120 [87721]
12. Response regulator for cyanobacterial phytochrome [75152]
  1. Synechocystis sp. PCC 6803, RCP1 [TaxId: 1148] [75153] (2)
    1. 1i3c
      complexed with mse, so4
      1. chain a [71112]
      2. chain b [71113]
    2. 1jlk
      mn(2+)-bound form
      complexed with mn, so4
      1. chain a [71727]
      2. chain b [71728]
  2. Calothrix sp. pcc 7601, RcpA [TaxId: 1188] [102226] (1)
    1. 1k68
      phosphorylated
      complexed with mg, phd
      1. chain a [90943]
      2. chain b [90944]
  3. Calothrix sp. pcc 7601, RcpB [TaxId: 1188] [102227] (1)
    1. 1k66
      complexed with bme
      1. chain a [90941]
      2. chain b [90942]
13. Cell division response regulator DivK [82342]
  1. Caulobacter crescentus [TaxId: 155892] [82343] (5)
    1. 1mb3
      complexed with mg
      1. chain a [78907]
    2. 1m5t
      1. chain a [78660]
    3. 1mav
      complexed with mn
      1. chain a [78893]
    4. 1m5u
      1. chain a [78661]
    5. 1mb0
      complexed with mn
      1. chain a [78900]
14. Response regulator Sin1 [102228]
  1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [102229] (3)
    1. 2r25
      automatically matched to d1oxkb_
      complexed with bef, mg, na
      1. region b:1087-1214 [151530]
    2. 1oxk
      complexed with so4
      1. chain b [93691]
      2. chain d [93693]
      3. chain f [93695]
      4. chain h [93697]
      5. chain j [93699]
      6. chain l [93701]
    3. 1oxb
      complexed with so4
      1. chain b [93682]
15. Transcriptional activator sigm54 (NtrC1), N-terminal domain [102230]
  1. Aquifex aeolicus [TaxId: 63363] [102231] (2)
    1. 1ny5
      complexed with adp, gol, mg, po4
      1. region a:1-137 [92317]
      2. region b:1-137 [92319]
    2. 1zy2
      complexed with mg, phd
      1. region a:1-136 [125811]
16. DNA-binding response regulator MicA, N-terminal domain [102232]
  1. Streptococcus pneumoniae [TaxId: 1313] [102233] (11)
    1. 2a9p
      automatically matched to d1nxoa_
      complexed with bef, mn
      1. region a:2-118 [126445]
    2. 2a9o
      automatically matched to d1nxoa_
      complexed with bef, mn
      1. region a:2-118 [126444]
    3. 1nxo
      1. chain a [92306]
    4. 1nxp
      complexed with phs
      1. chain a [92307]
    5. 1nxx
      1. chain a [92312]
    6. 1nxw
      complexed with acy
      1. chain a [92311]
    7. 1nxs
      1. chain a [92308]
    8. 1nxv
      1. chain a [92310]
    9. 2a9r
      automatically matched to d1nxoa_
      complexed with mg, phd, xe
      1. region a:2-118 [126447]
    10. 1nxt
      complexed with phd, xe
      1. chain a [92309]
    11. 2a9q
      automatically matched to d1nxoa_
      1. region a:2-118 [126446]
17. Probable two-component system transcriptional regulator Rv1626 [110464]
  contains extra C-terminal all-alpha subdomain (144-20), 3-helical bundle
  1. Mycobacterium tuberculosis [TaxId: 1773] [110465] (2)
    SQ O06143
    1. 1s8n
      Structural genomics target
      complexed with azi
      1. chain a [105374]
    2. 1sd5
      Structural genomics target
      complexed with iod
      1. chain a [105430]
18. Response regulator PleD, receiver domain [117472]
  duplication: tandem repeat of 2 CheY-like domains
  1. Caulobacter crescentus [TaxId: 155892] [117473] (5)
    SQ Q9A5I5
    1. 1w25
      complexed with 5gp, mg, zn
      1. region a:2-140 [114090]
      2. region a:141-293 [114091]
      3. region b:2-140 [114093]
      4. region b:141-293 [114094]
    2. 2v0n
      automatically matched to d1w25a1
      complexed with 5gp, bef, cl, gav, mg, so4
      1. region a:2-140 [152365]
    3. 2v0n
      automatically matched to d1w25a2
      complexed with 5gp, bef, cl, gav, mg, so4
      1. region a:141-293 [152366]
    4. 2v0n
      automatically matched to d1w25a1
      complexed with 5gp, bef, cl, gav, mg, so4
      1. region b:2-140 [152368]
    5. 2v0n
      automatically matched to d1w25a2
      complexed with 5gp, bef, cl, gav, mg, so4
      1. region b:141-293 [152369]
19. Sensor kinase protein RcsC, C-terminal domain [142023]
  1. Escherichia coli [TaxId: 562] [142024] (2)
    SQ P14376 817-949
    1. 2ayx
      1. region a:817-949 [127574]
    2. 2ayz
      C-terminal domain only
      1. region a:817-949 [127577]
20. Transcriptional regulatory protein KdpE, N-terminal domain [142025]
  1. Escherichia coli [TaxId: 562] [142026] (4)
    SQ P21866 2-120
    1. 1zh2
      complexed with ca; mutant
      1. region a:2-120 [125069]
    2. 1zh2
      automatically matched to 1ZH2 A:2-120
      complexed with ca; mutant
      1. region b:2-120 [125070]
    3. 1zh4
      automatically matched to 1ZH2 A:2-120
      complexed with bef, mg; mutant
      1. region a:2-120 [125071]
    4. 1zh4
      automatically matched to 1ZH2 A:2-120
      complexed with bef, mg; mutant
      1. region b:2-120 [125072]
21. Response regulatory protein StyR, N-terminal domain [142027]
  1. Pseudomonas fluorescens [TaxId: 294] [142028] (2)
    SQ O30989 3-130
    1. 1yio
      complexed with hg, mg
      1. region a:3-130 [123327]
    2. 1zn2
      automatically matched to 1YIO A:3-130
      complexed with mg
      1. region a:3-130 [125372]
22. Hypothetical protein BH3024 [142029]
  1. Bacillus halodurans [TaxId: 86665] [142030] (1)
    SQ Q9K8I2 2-119
    1. 2b4a
      complexed with edo
      1. region a:2-119 [127817]
23. Transcriptional regulatory protein PrrA, N-terminal domain [142031]
  1. Mycobacterium tuberculosis [TaxId: 1773] [142032] (4)
    SQ P0A5Z6 7-127
    1. 1ys7
      automatically matched to 1YS6 A:7-127
      complexed with act, gol, mg, trs
      1. region a:7-127 [123962]
    2. 1ys7
      automatically matched to 1YS6 A:7-127
      complexed with act, gol, mg, trs
      1. region b:7-127 [123964]
    3. 1ys6
      complexed with ca, gol
      1. region a:7-127 [123958]
    4. 1ys6
      automatically matched to 1YS6 A:7-127
      complexed with ca, gol
      1. region b:7-127 [123960]
24. TorCAD operon transcriptional regulator TorD, N-terminal domain [142033]
  1. Escherichia coli [TaxId: 562] [142034] (4)
    SQ P38684 2-121
    1. 1zgz
      complexed with gol, so4; mutant
      1. region a:2-121 [125065]
    2. 1zgz
      automatically matched to 1ZGZ A:2-121
      complexed with gol, so4; mutant
      1. region b:2-121 [125066]
    3. 1zgz
      automatically matched to 1ZGZ A:2-121
      complexed with gol, so4; mutant
      1. region c:2-121 [125067]
    4. 1zgz
      automatically matched to 1ZGZ A:2-121
      complexed with gol, so4; mutant
      1. region d:2-121 [125068]
25. Aerobic respiration control protein ArcA, N-terminal domain [142035]
  1. Escherichia coli [TaxId: 562] [142036] (4)
    SQ P0A9Q1 2-122
    1. 1xhf
      automatically matched to 1XHE A:2-122
      complexed with bef, bf2, bf4, mg; mutant
      1. region a:2-122 [122003]
    2. 1xhf
      automatically matched to 1XHE A:2-122
      complexed with bef, bf2, bf4, mg; mutant
      1. region b:2-122 [122004]
    3. 1xhe
      mutant
      1. region a:2-122 [122001]
    4. 1xhe
      automatically matched to 1XHE A:2-122
      mutant
      1. region b:2-122 [122002]
Receiver domain of the ethylene receptor [52194] (1)
1. Receiver domain of the ethylene receptor [52195]
  1. Thale cress (Arabidopsis thaliana) [TaxId: 3702] [52196] (1)
    1. 1dcf
      1. chain a [31124]
Positive regulator of the amidase operon AmiR [52197] (1)
1. Positive regulator of the amidase operon AmiR [52198]
  contains coiled coil and small all-alpha subdomains in the C-terminal extension
  1. Pseudomonas aeruginosa [TaxId: 287] [52199] (1)
    1. 1qo0
      1. chain d [31125]
      2. chain e [31126]
Ornithine decarboxylase N-terminal "wing" domain [52252] (1)
1. Ornithine decarboxylase N-terminal "wing" domain [52253]
  1. Lactobacillus sp., strain 30a [TaxId: 1591] [52254] (2)
    1. 1c4k
      complexed with gtp, plp; mutant
      1. region a:1-107 [31273]
    2. 1ord
      complexed with plp
      1. region a:1-107 [31274]
      2. region b:1-107 [31275]
N-terminal domain of the circadian clock protein KaiA [82344] (1)
lacks canonical receiver domains features
1. N-terminal domain of the circadian clock protein KaiA [82345]
  1. Synechococcus elongatus [TaxId: 32046] [82346] (3)
    SQ Q79PF6
    1. 1r8j
      structured linker 136-176 in swapped dimer
      1. region a:1-135 [104848]
      2. region b:1-135 [104850]
    2. 1m2e
      CASP5
      1. chain a [78478]
    3. 1m2f
      1. chain a [78479]
RcsC linker domain-like [142037] (1)
PfamB 016190; probable rudiment CheY-like domain; precedes the C-terminal CheY-related domain of similar structure
1. Sensor kinase protein RcsC [142038]
  1. Escherichia coli [TaxId: 562] [142039] (2)
    SQ P14376 700-816
    1. 2ayy
      linker domain only
      1. region a:700-816 [127576]
    2. 2ayx
      1. region a:700-816 [127575]
AF1403 C-terminal domain-like [142040] (1)
1. Hypothetical protein AF1403, C-terminal domain [142041]
  1. Archaeon Archaeoglobus fulgidus [TaxId: 2234] [142042] (3)
    SQ O28869 79-217
    1. 1y7p
      complexed with rip, zn
      1. region a:79-217 [122708]
    2. 1y7p
      automatically matched to 1Y7P A:79-217
      complexed with rip, zn
      1. region b:79-215 [122710]
    3. 1y7p
      automatically matched to 1Y7P A:79-217
      complexed with rip, zn
      1. region c:79-217 [122712]