Structural Classification of Proteins
home mail help root up expand collapse

Family: Tetrahydrofolate dehydrogenase/cyclohydrolase

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: Aminoacid dehydrogenase-like, N-terminal domain [53222]
    core: 3 layers: a/b/a; parallel beta-sheet of 4 strands; 2134
  4. Superfamily: Aminoacid dehydrogenase-like, N-terminal domain [53223]
    link to SUPERFAMILY database - Superfamily
  5. Family: Tetrahydrofolate dehydrogenase/cyclohydrolase [53235]

Protein Domains:

  1. Tetrahydrofolate dehydrogenase/cyclohydrolase [53236]
    the two-domain organization is similar to that of aminoacid dehydrogenases, but both domains are truncated
    1. Human (Homo sapiens) [TaxId: 9606] [53237] (4)
      1. 1a4i picpicxref
        complexed with ndp
        1. region a:2-126 [33926] picpiclink
        2. region b:2-126 [33927] picpiclink
      2. 1dig picpicxref
        complexed with act, l37, nap
        1. region a:2-126 [33930] picpiclink
        2. region b:1002-1126 [33931] picpiclink
      3. 1dia picpicxref
        complexed with l24, nap
        1. region a:2-126 [33928] picpiclink
        2. region b:1002-1126 [33929] picpiclink
      4. 1dib picpicxref
        complexed with l34, nap
        1. region a:2-126 [33932] picpiclink
        2. region b:1002-1126 [33933] picpiclink
    2. Escherichia coli [TaxId: 562] [53238] (1)
      1. 1b0a picpicxref
        1. region a:2-122 [33934] picpiclink
    3. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [53239] (2)
      1. 1edz picpicxref
        1. region a:3-148 [33935] picpiclink
      2. 1ee9 picpicxref
        complexed with nad
        1. region a:3-148 [33936] picpiclink
Enter search key:
MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk