Structural Classification of Proteins
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Family: Phosphoglucose isomerase, PGI

permutation of the double-SIS domain fold

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: SIS domain [53696]
    3 layers: a/b/a; parallel beta-sheet of 5 strands, order 21345
  4. Superfamily: SIS domain [53697]
    link to SUPERFAMILY database - Superfamily
  5. Family: Phosphoglucose isomerase, PGI [53701]
    permutation of the double-SIS domain fold

Protein Domains:

  1. Phosphoglucose isomerase, PGI [53702]
    moonlights as neuroleukin, autocrine motility factor, and differentiation mediator
    1. Rabbit (Oryctolagus cuniculus) [TaxId: 9986] [53703] (8)
      1. 1hm5 picpic
        1. chain a [76717] picpiclink
        2. chain b [76718] picpiclink
      2. 1g98 picpic
        complexed with 5-phosphoarabinonate, a transition state analogue
        complexed with pa5
        1. chain a [60396] picpiclink
        2. chain b [60397] picpiclink
      3. 1xtb picpic
        automatically matched to d1hm5a_
        complexed with s6p
        1. region a:1-556 [122295] picpiclink
      4. 1xtb picpic
        automatically matched to d1hm5a_
        complexed with s6p
        1. region b:1001-1556 [122296] picpiclink
      5. 1koj picpic
        complexed with pan
        1. chain a [72821] picpiclink
        2. chain b [72822] picpiclink
      6. 1hox picpic
        complexed with f6p
        1. chain a [61108] picpiclink
        2. chain b [61109] picpiclink
      7. 1n8t picpic
        1. chain a [85454] picpiclink
        2. chain b [85455] picpiclink
      8. 1dqr picpic
        1. chain a [35305] picpiclink
        2. chain b [35306] picpiclink
    2. Human (Homo sapiens) [TaxId: 9606] [64176] (5)
      1. 1iat picpic
        complexed with bme, sul
        1. chain a [62123] picpiclink
      2. 1jiq picpic
        1. chain a [71689] picpiclink
        2. chain b [71690] picpiclink
        3. chain c [71691] picpiclink
        4. chain d [71692] picpiclink
      3. 1jlh picpic
        1. chain a [77131] picpiclink
        2. chain b [77132] picpiclink
        3. chain c [77133] picpiclink
        4. chain d [77134] picpiclink
      4. 1iri picpic
        complexed with e4p
        1. chain a [71343] picpiclink
        2. chain b [71344] picpiclink
        3. chain c [71345] picpiclink
        4. chain d [71346] picpiclink
      5. 1nuh picpic
        complexed with pa5, so4
        1. chain a [80733] picpiclink
    3. Pig (Sus scrofa) [TaxId: 9823] [75316] (2)
      1. 1gzd picpic
        complexed with so4
        1. chain a [70804] picpiclink
      2. 1gzv picpic
        complexed with pa5
        1. chain a [76432] picpiclink
    4. Bacillus stearothermophilus [TaxId: 1422] [53704] (4)
      1. 1c7q picpic
        complexed with be1
        1. chain a [35307] picpiclink
      2. 1b0z picpic
        1. chain a [35309] picpiclink
      3. 2pgi picpic
        1. chain a [35308] picpiclink
      4. 1c7r picpic
        complexed with pa5
        1. chain a [35310] picpiclink
    5. Leishmania mexicana [TaxId: 5665] [110728] (2)
      SQ P42861
      1. 1q50 picpic
        1. chain a [104535] picpiclink
      2. 1t10 picpic
        complexed with f6p
        1. chain a [106235] picpiclink
    6. Mouse (Mus musculus) [TaxId: 10090] [117732] (3)
      SQ P06745
      1. 1u0f picpic
        complexed with bme, g6p, g6q, gol, so4
        1. chain a [112912] picpiclink
        2. chain b [112913] picpiclink
      2. 1u0e picpic
        complexed with bme, gol, so4
        1. chain a [112910] picpiclink
        2. chain b [112911] picpiclink
      3. 1u0g picpic
        complexed with bme, e4p, gol, so4
        1. chain a [112914] picpiclink
        2. chain b [112915] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk