Structural Classification of Proteins
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Superfamily: L domain-like

less regular structure consisting of variable repeats
link to SUPERFAMILY database - Superfamily

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) [52046]
    2 curved layers, a/b; parallel beta-sheet; order 1234...N; there are sequence similarities between different superfamilies
  4. Superfamily: L domain-like [52058]
    less regular structure consisting of variable repeats
    link to SUPERFAMILY database - Superfamily

Families:

  1. Internalin LRR domain [52059] (3)
    capped at the N-end with a truncated EF-hand subdomain
    1. Internalin A [82324]
      1. Listeria monocytogenes [TaxId: 1639] [82325] (7) picpic
    2. Internalin B [52060]
      1. Listeria monocytogenes [TaxId: 1639] [52061] (9) picpic
    3. Internalin H [69431]
      1. Listeria monocytogenes [TaxId: 1639] [69432] (1) picpic
  2. Leucine rich effector protein YopM [69433] (1)
    1. Leucine rich effector protein YopM [69434]
      1. Yersinia pestis [TaxId: 632] [69435] (2) picpic
  3. Ngr ectodomain-like [75142] (6)
    1. von Willebrand factor binding domain of glycoprotein Ib alpha [75143]
      1. Human (Homo sapiens) [TaxId: 9606] [75144] (9) picpic
    2. Reticulon 4 receptor (Nogo-66 receptor, Ngr) [89567]
      1. Human (Homo sapiens) [TaxId: 9606] [89568] (2) picpic
    3. Slit [117461]
      1. Fruit fly (Drosophila melanogaster) [TaxId: 7227] [117462] (1) picpic
        SQ P24014 542-733
    4. Decorin [117463]
      1. Cow (Bos taurus) [TaxId: 9913] [117464] (3) picpic
        SQ P21793 52-356
    5. High affinity nerve growth factor receptor, N-terminal domain [141992]
      1. Human (Homo sapiens) [TaxId: 9606] [141993] (2) picpic
        SQ P04629 36-191
    6. Follicle-stimulating hormone receptor [159450]
      1. Human (Homo sapiens) [TaxId: 9606] [159451] (1) picpic
        SQ P23945 18-259
  4. Polygalacturonase inhibiting protein PGIP [89569] (1)
    1. Polygalacturonase inhibiting protein PGIP [89570]
      1. Kidney bean (Phaseolus vulgaris) [TaxId: 3885] [89571] (1) picpic
  5. Rab geranylgeranyltransferase alpha-subunit, C-terminal domain [52062] (1)
    1. Rab geranylgeranyltransferase alpha-subunit, C-terminal domain [52063]
      1. Rat (Rattus norvegicus) [TaxId: 10116] [52064] (2) picpic
  6. mRNA export factor tap [52065] (1)
    1. mRNA export factor tap [52066]
      1. Human (Homo sapiens) [TaxId: 9606] [52067] (8) picpic
  7. U2A'-like [52068] (1)
    duplication: consists of 5-6 partly irregular repeats
    1. Splicesomal U2A' protein [52069]
      1. Human (Homo sapiens) [TaxId: 9606] [52070] (1) picpic
  8. L domain [52071] (6)
    1. Type 1 insulin-like growth factor receptor extracellular domain [52072]
      1. Human (Homo sapiens) [TaxId: 9606] [52073] (1) picpic
        L1 and L2 domains
    2. Receptor protein-tyrosine kinase Erbb-3 extracellular domain [75145]
      1. Human (Homo sapiens) [TaxId: 9606] [75146] (1) picpic
    3. EGF receptor extracellular domain [82326]
      1. Human (Homo sapiens) [TaxId: 9606] [82327] (15) picpic
    4. Protooncoprotein Her2 extracellular domain [82328]
      1. Human (Homo sapiens) [TaxId: 9606] [82329] (2) picpic
      2. Rat (Rattus norvegicus) [TaxId: 10116] [82330] (1) picpic
    5. Insulin receptor [159452]
      1. Human (Homo sapiens) [TaxId: 9606] [159453] (2) picpic
        SQ P06213 31-183! SQ P06213 339-494
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk