Structural Classification of Proteins
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Family: Prokaryotic proteases

Lineage:

  1. Root: scop
  2. Class: All beta proteins [48724]
  3. Fold: Trypsin-like serine proteases [50493]
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. Superfamily: Trypsin-like serine proteases [50494]
    link to SUPERFAMILY database - Superfamily
  5. Family: Prokaryotic proteases [50495]

Protein Domains:

  1. Achromobacter protease [50496]
    1. Achromobacter lyticus, strain m497-1 [TaxId: 224] [50497] (2)
      1. 1arb picpic
        1. chain a [25766] picpiclink
      2. 1arc picpic
        complexed with tck
        1. chain a [25767] picpiclink
  2. alpha-Lytic protease [50498]
    1. Lysobacter enzymogenes, 495 [TaxId: 69] [50499] (41)
      1. 2h5c picpic
        automatically matched to d1p01a_
        complexed with gol, so4
        1. region a:15a-245 [136145] picpiclink
      2. 1ssx picpic
        complexed with gol, so4
        1. chain a [98978] picpiclink
      3. 2h5d picpic
        automatically matched to d1p01a_
        complexed with b2v, gol, msu, so4
        1. region a:15a-245 [136146] picpiclink
      4. 1qrw picpic
        complexed with gol, so4; mutant
        1. chain a [25769] picpiclink
      5. 1qq4 picpic
        complexed with gol, so4; mutant
        1. chain a [25768] picpiclink
      6. 1tal picpic
        complexed with so4, tam
        1. chain a [25770] picpiclink
      7. 2ull picpic
        complexed with so4, tam
        1. chain a [25773] picpiclink
      8. 1qrx picpic
        complexed with gol, so4
        1. chain a [25771] picpiclink
      9. 2alp picpic
        complexed with so4
        1. chain a [25772] picpiclink
      10. 1p12 picpic
        complexed with boc, lac, pva, so4
        1. chain e [25774] picpiclink
      11. 1p11 picpic
        complexed with boc, lac, pva, so4
        1. chain e [25775] picpiclink
      12. 1gbj picpic
        complexed with so4; mutant
        1. chain a [25776] picpiclink
      13. 1p01 picpic
        complexed with b2v, boc, so4
        1. chain a [25778] picpiclink
      14. 1p02 picpic
        complexed with b2a, so4
        1. chain a [25777] picpiclink
      15. 6lpr picpic
        complexed with bno, msu, so4; mutant
        1. chain a [25779] picpiclink
      16. 3pro picpicxref
        complexed with 2ab; mutant
        1. chain a [25780] picpiclink
        2. chain b [25781] picpiclink
      17. 1gbb picpic
        complexed with b2a, so4; mutant
        1. chain a [25785] picpiclink
      18. 1gba picpic
        complexed with so4; mutant
        1. chain a [25783] picpiclink
      19. 1gbk picpic
        complexed with b2a, so4; mutant
        1. chain a [25790] picpiclink
      20. 1gbc picpic
        complexed with ble, so4; mutant
        1. chain a [25788] picpiclink
      21. 7lpr picpic
        complexed with ble, msu, so4; mutant
        1. chain a [25782] picpiclink
      22. 1gbf picpic
        complexed with b2a, so4; mutant
        1. chain a [25784] picpiclink
      23. 1gbd picpic
        complexed with b2f, so4; mutant
        1. chain a [25787] picpiclink
      24. 5lpr picpic
        complexed with b2a, msu, so4; mutant
        1. chain a [25789] picpiclink
      25. 1gbl picpic
        complexed with ble, so4; mutant
        1. chain a [25794] picpiclink
      26. 3lpr picpic
        complexed with bno, msu, so4; mutant
        1. chain a [25791] picpiclink
      27. 1p03 picpic
        complexed with b2v, so4
        1. chain a [25792] picpiclink
      28. 9lpr picpic
        complexed with ble, msu, so4
        1. chain a [25795] picpiclink
      29. 2lpr picpic
        complexed with b2v, msu, so4; mutant
        1. chain a [25798] picpiclink
      30. 1boq picpic
        complexed with so4; mutant
        1. chain a [25797] picpiclink
      31. 1p09 picpic
        complexed with so4; mutant
        1. chain a [25793] picpiclink
      32. 1p05 picpic
        complexed with bno, so4
        1. chain a [25786] picpiclink
      33. 1gbm picpic
        complexed with b2f, so4; mutant
        1. chain a [25799] picpiclink
      34. 1gbh picpic
        complexed with ble, so4; mutant
        1. chain a [25800] picpiclink
      35. 1gbi picpic
        complexed with b2f, so4; mutant
        1. chain a [25802] picpiclink
      36. 8lpr picpic
        complexed with b1f, msu, so4; mutant
        1. chain a [25796] picpiclink
      37. 1p10 picpic
        complexed with b2v, so4; mutant
        1. chain a [25801] picpiclink
      38. 1gbe picpic
        complexed with so4; mutant
        1. chain a [25803] picpiclink
      39. 1p06 picpic
        complexed with b1f, so4
        1. chain a [25804] picpiclink
      40. 1p04 picpic
        complexed with b2i, so4
        1. chain a [25805] picpiclink
      41. 4pro picpicxref
        mutant
        1. chain a [25806] picpiclink
        2. chain b [25807] picpiclink
  3. Protease A [50500]
    1. Streptomyces griseus, strain k1 [TaxId: 1911] [50501] (5)
      1. 2sga picpic
        1. chain a [25808] picpiclink
      2. 3sga picpic
        complexed with pha
        1. chain e [25809] picpiclink
      3. 4sga picpic
        1. chain e [25811] picpiclink
      4. 5sga picpic
        1. chain e [25812] picpiclink
      5. 1sgc picpic
        complexed with cst
        1. chain a [25810] picpiclink
  4. Glutamic acid-specific protease [50502]
    1. Streptomyces griseus [TaxId: 1911] [50503] (1)
      1. 1hpg picpic
        complexed with boc
        1. chain a [25813] picpiclink
  5. Trypsin [50504]
    1. Streptomyces griseus, strain k1 [TaxId: 1911] [50505] (3)
      1. 1os8 picpic
        complexed with ca, so4
        1. chain a [93481] picpiclink
      2. 1sgt picpic
        complexed with ca
        1. chain a [25814] picpiclink
      3. 1oss picpic
        complexed with ben, ca, so4; mutant
        1. chain a [93499] picpiclink
  6. Serine proteinase [50506]
    1. Streptomyces fradiae [TaxId: 1906] [50507] (1)
      1. 2sfa picpic
        1. chain a [25815] picpiclink
  7. Protease B [50508]
    1. Streptomyces griseus, strain k1 [TaxId: 1911] [50509] (29)
      Streptogrisin B
      1. 2qaa picpic
        automatically matched to d1sgde_
        complexed with acy, cl, edo, epe, gol, leu, so4, tyr
        1. region a:16-242 [150201] picpiclink
      2. 2qaa picpic
        automatically matched to d1sgde_
        complexed with acy, cl, edo, epe, gol, leu, so4, tyr
        1. region b:16-242 [150202] picpiclink
      3. 2qa9 picpic
        automatically matched to d1sgde_
        complexed with cl, edo, gol, so4
        1. region e:16-242 [150200] picpiclink
      4. 1sgp picpicxref
        complexed with po4; mutant
        1. chain e [25816] picpiclink
      5. 1ct4 picpicxref
        1. chain e [25819] picpiclink
      6. 1ct2 picpicxref
        1. chain e [25821] picpiclink
      7. 2nu2 picpicxref
        automatically matched to d1sgde_
        mutant
        1. region e:16-242 [138599] picpiclink
      8. 2sgf picpicxref
        complexed with po4; mutant
        1. chain e [100861] picpiclink
      9. 2nu4 picpicxref
        automatically matched to d1sgde_
        mutant
        1. region e:16-242 [138602] picpiclink
      10. 2nu3 picpicxref
        automatically matched to d1sgde_
        mutant
        1. region e:16-242 [138600] picpiclink
      11. 3sgb picpicxref
        1. chain e [25817] picpiclink
      12. 1ds2 picpicxref
        complexed with 1lu; mutant
        1. chain e [25822] picpiclink
      13. 2sgq picpicxref
        complexed with po4; mutant
        1. chain e [100863] picpiclink
      14. 2nu1 picpicxref
        automatically matched to d1sgde_
        mutant
        1. region e:16-242 [138598] picpiclink
      15. 1ct0 picpicxref
        1. chain e [25823] picpiclink
      16. 2gkv picpic
        automatically matched to d1sgde_
        mutant
        1. region e:16-242 [135335] picpiclink
      17. 1sgr picpicxref
        complexed with po4; mutant
        1. chain e [25818] picpiclink
      18. 1sgd picpicxref
        complexed with po4; mutant
        1. chain e [98851] picpiclink
      19. 1sge picpicxref
        complexed with po4; mutant
        1. chain e [98853] picpiclink
      20. 1sgy picpicxref
        complexed with po4; mutant
        1. chain e [98870] picpiclink
      21. 1sgn picpicxref
        complexed with po4; mutant
        1. chain e [98855] picpiclink
      22. 2nu0 picpicxref
        automatically matched to d1sgde_
        mutant
        1. region e:16-242 [138597] picpiclink
      23. 1sgq picpicxref
        complexed with po4; mutant
        1. chain e [25820] picpiclink
      24. 3sgq picpicxref
        complexed with po4; mutant
        1. chain e [100869] picpiclink
      25. 2sge picpicxref
        complexed with k, po4; mutant
        1. chain e [100859] picpiclink
      26. 4sgb picpicxref
        complexed with ca, so4
        1. chain e [25824] picpiclink
      27. 1cso picpicxref
        1. chain e [25826] picpiclink
      28. 2sgp picpicxref
        complexed with po4; mutant
        1. chain e [25825] picpiclink
      29. 2sgd picpicxref
        complexed with k, po4; mutant
        1. chain e [100857] picpiclink
  8. Epidermolytic (exfoliative) toxin A [50510]
    probable glutamic acid-specific protease
    1. Staphylococcus aureus [TaxId: 1280] [50511] (4)
      1. 1agj picpic
        CASP2
        1. chain a [25827] picpiclink
        2. chain b [25828] picpiclink
      2. 1exf picpic
        1. chain a [25829] picpiclink
      3. 1due picpic
        mutant
        1. chain a [76140] picpiclink
      4. 1dua picpic
        1. chain a [76139] picpiclink
  9. Exfoliative toxin B [50512]
    1. Staphylococcus aureus [TaxId: 1280] [50513] (2)
      1. 1qtf picpic
        1. chain a [25830] picpiclink
      2. 1dt2 picpic
        1. chain a [76138] picpiclink
  10. V8 protease [101809]
    glutamic acid-specific protease
    1. Staphylococcus aureus [TaxId: 1280] [101810] (3)
      SQ P04188 69-284
      1. 2o8l picpic
        automatically matched to d1qy6a_
        complexed with k
        1. region a:1-216 [138932] picpiclink
      2. 1qy6 picpic
        complexed with k
        1. chain a [96574] picpiclink
      3. 1wcz picpic
        complexed with zn
        1. chain a [109229] picpiclink
  11. Glutamyl endopeptidase [101811]
    1. Bacillus intermedius [TaxId: 1400] [101812] (2)
      1. 1p3c picpic
        1. chain a [93996] picpiclink
      2. 1p3e picpic
        complexed with mpd
        1. chain a [93997] picpiclink
  12. Protease Do (DegP, HtrA), catalytic domain [74969]
    1. Escherichia coli [TaxId: 562] [74970] (14)
      1. 1ky9 picpicxref
        complexed with mse; mutant
        1. region a:11-259 [73199] picpiclink
        2. region b:11-259 [73202] picpiclink
      2. 3cs0 picpicxrefxref
        automatically matched to d1ky9a2
        1. region a:11-259 [156953] picpiclink
      3. 2zle picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1ky9a2
        1. region a:1-214 [154634] picpiclink
      4. 2zle picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1ky9a2
        1. region b:397-610 [154637] picpiclink
      5. 2zle picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1ky9a2
        1. region c:793-1006 [154640] picpiclink
      6. 2zle picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1ky9a2
        1. region e:1535-1748 [154643] picpiclink
      7. 2zle picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1ky9a2
        1. region f:1931-2144 [154646] picpiclink
      8. 2zle picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1ky9a2
        1. region g:2327-2540 [154649] picpiclink
      9. 2zle picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1ky9a2
        1. region h:2723-2936 [154652] picpiclink
      10. 2zle picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1ky9a2
        1. region i:3119-3332 [154655] picpiclink
      11. 2zle picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1ky9a2
        1. region j:3515-3728 [154658] picpiclink
      12. 2zle picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1ky9a2
        1. region k:3911-4124 [154661] picpiclink
      13. 2zle picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1ky9a2
        1. region l:4307-4520 [154664] picpiclink
      14. 2zle picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1ky9a2
        1. region m:4703-4916 [154667] picpiclink
    2. Thermotoga maritima [TaxId: 2336] [89339] (1)
      1. 1l1j picpic
        catalytic domain only
        1. chain a [84516] picpiclink
        2. chain b [84517] picpiclink
  13. Mitochondrial serine protease HtrA2, catalytic domain [74971]
    1. Human (Homo sapiens) [TaxId: 9606] [74972] (1)
      1. 1lcy picpicxref
        mutant
        1. region a:6-210 [73835] picpiclink
  14. Stress sensor protease DegS, catalytic domain [110236]
    1. Escherichia coli [TaxId: 562] [110237] (31)
      SQ P31137 37-354 ! SQ P31137
      1. 2qf3 picpic
        automatically matched to d1sota2
        complexed with po4
        1. region a:43-252 [150724] picpiclink
      2. 2qf3 picpic
        automatically matched to d1sota2
        complexed with po4
        1. region b:43-251 [150725] picpiclink
      3. 2qf3 picpic
        automatically matched to d1sota2
        complexed with po4
        1. region c:43-251 [150726] picpiclink
      4. 2rce picpic
        automatically matched to d1sota2
        1. region a:43-252 [151876] picpiclink
      5. 2rce picpic
        automatically matched to d1sota2
        1. region b:43-252 [151877] picpiclink
      6. 2rce picpic
        automatically matched to d1sota2
        1. region c:43-252 [151878] picpiclink
      7. 2rce picpic
        automatically matched to d1sota2
        1. region d:43-252 [151879] picpiclink
      8. 2rce picpic
        automatically matched to d1sota2
        1. region e:43-251 [151880] picpiclink
      9. 2rce picpic
        automatically matched to d1sota2
        1. region f:43-252 [151881] picpiclink
      10. 2rce picpic
        automatically matched to d1sota2
        1. region g:43-252 [151882] picpiclink
      11. 2rce picpic
        automatically matched to d1sota2
        1. region h:43-251 [151883] picpiclink
      12. 2rce picpic
        automatically matched to d1sota2
        1. region i:43-251 [151884] picpiclink
      13. 1sot picpicxref
        1. region a:42-254 [105853] picpiclink
        2. region b:42-254 [105855] picpiclink
        3. region c:42-254 [105857] picpiclink
      14. 2qf0 picpic
        automatically matched to d1sota2
        1. region a:43-252 [150715] picpiclink
      15. 2qf0 picpic
        automatically matched to d1sota2
        1. region b:43-252 [150716] picpiclink
      16. 2qf0 picpic
        automatically matched to d1sota2
        1. region c:43-252 [150717] picpiclink
      17. 2qf0 picpic
        automatically matched to d1sota2
        1. region d:43-252 [150718] picpiclink
      18. 2qf0 picpic
        automatically matched to d1sota2
        1. region e:43-251 [150719] picpiclink
      19. 2qf0 picpic
        automatically matched to d1sota2
        1. region f:43-252 [150720] picpiclink
      20. 2qf0 picpic
        automatically matched to d1sota2
        1. region g:43-250 [150721] picpiclink
      21. 2qf0 picpic
        automatically matched to d1sota2
        1. region h:43-252 [150722] picpiclink
      22. 2qf0 picpic
        automatically matched to d1sota2
        1. region i:43-252 [150723] picpiclink
      23. 2r3u picpic
        automatically matched to d1sota2
        mutant
        1. region a:42-251 [151558] picpiclink
      24. 2r3y picpicxrefxrefxref
        automatically matched to d1te0a2
        1. region a:43-254 [151566] picpiclink
      25. 2r3u picpic
        automatically matched to d1sota2
        mutant
        1. region b:42-251 [151559] picpiclink
      26. 2r3u picpic
        automatically matched to d1sota2
        mutant
        1. region c:42-251 [151560] picpiclink
      27. 2r3y picpicxrefxrefxref
        automatically matched to d1te0a2
        1. region b:43-254 [151568] picpiclink
      28. 2r3y picpicxrefxrefxref
        automatically matched to d1te0a2
        1. region c:43-254 [151570] picpiclink
      29. 1soz picpicxref
        1. region a:42-254 [105860] picpiclink
        2. region b:42-254 [105862] picpiclink
        3. region c:42-254 [105864] picpiclink
      30. 1te0 picpicxref
        1. region a:37-254 [112401] picpiclink
        2. region b:37-254 [112403] picpiclink
      31. 1vcw picpicxref
        1. region a:42-254 [108511] picpiclink
        2. region b:42-254 [108513] picpiclink
        3. region c:42-254 [108515] picpiclink
  15. Protease PepD [141383]
    1. Mycobacterium tuberculosis [TaxId: 1773] [141384] (6)
      SQ O53896 154-374
      Rv0983
      1. 2z9i picpicxrefxrefxref
        automatically matched to d1y8ta2
        1. region a:6-226 [154249] picpiclink
      2. 2z9i picpicxrefxrefxref
        automatically matched to d1y8ta2
        1. region b:6-226 [154251] picpiclink
      3. 2z9i picpicxrefxrefxref
        automatically matched to d1y8ta2
        1. region c:6-226 [154253] picpiclink
      4. 1y8t picpicxrefxrefxref
        1. region a:6-226 [122764] picpiclink
      5. 1y8t picpicxrefxrefxref
        automatically matched to 1Y8T A:6-226
        1. region b:6-226 [122766] picpiclink
      6. 1y8t picpicxrefxrefxref
        automatically matched to 1Y8T A:6-226
        1. region c:6-226 [122768] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk