Structural Classification of Proteins

Superfamily: Translation proteins

: uperfamily

Lineage:

Root: scop
Class: All beta proteins [48724]
Fold: Reductase/isomerase/elongation factor common domain [50412]
barrel, closed; n=6, S=10; greek-key
Superfamily: Translation proteins [50447]
uperfamily

Families:

Elongation factors [50448] (18)
1. Elongation factor Tu (EF-Tu), domain 2 [50449]
  N-terminal domain is related to G proteins; C-terminal domain is (6,10) barrel of circularly permuted topology
  1. Escherichia coli [TaxId: 562] [50450] (8)
    SQ P02990
  2. Thermus aquaticus [TaxId: 271] [50451] (4)
  3. Thermus thermophilus [TaxId: 274] [50452] (9)
  4. Cow (Bos taurus), mitochondrial [TaxId: 9913] [50453] (2)
    SQ P49410 56-452
2. Elongation factor eEF-1alpha, domain 2 [50454]
  eukaryotic and archaeal homologue of EF-Tu
  1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [50455] (6)
  2. Archaeon Sulfolobus solfataricus [TaxId: 2287] [69276] (2)
    SQ P35021
3. Elongation factor G (EF-G), domain II [50456]
  1. Thermus thermophilus [TaxId: 274] [50457] (9)
  2. Thermus thermophilus, EF-G-2 [TaxId: 274] [141334] (2)
    SQ Q5SI76 268-370
    TTHA1498
4. Elongation factor 2 (eEF-2), domain II [82118]
  1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [82119] (22)
    SQ P32324
5. Initiation factor eIF2 gamma subunit, domain II [74962]
  1. Archaeon Pyrococcus abyssi [TaxId: 29292] [74963] (5)
  2. Archaeon Methanococcus jannaschii [TaxId: 2190] [101788] (1)
  3. Sulfolobus solfataricus [TaxId: 2287] [141335] (6)
    SQ Q980A5 207-320
6. Initiation factor IF2/eIF5b, domains 2 and 4 [50458]
  the C-terminal domain 4 has the same fold as domain 2; it probably binds fMet-tRNAfmet
  1. Archaeon Methanobacterium thermoautotrophicum [TaxId: 145262] [50459] (3)
  2. Bacillus stearothermophilus [TaxId: 1422] [50460] (1)
7. Eukaryotic peptide chain release factor ERF2, post-G domain [110225]
  1. Fission yeast (Schizosaccharomyces pombe) [TaxId: 4896] [110226] (3)
    SQ O74718
8. Hypothetical protein PF0907 [110227]
  stand-alone protein related to this domain
  1. Pyrococcus furiosus [TaxId: 2261] [110228] (1)
    SQ Q8U2D2 18-108
9. Elongation factor SelB, domains 2 and 4 [117218]
  EF-Tu homologue, contains extra C-terminal domain (domain 4) of the same fold as the postG domain 2
  1. Methanococcus maripaludis [TaxId: 39152] [117219] (3)
    SQ Q8J307
10. Sulfate adenylate transferase subunit cysN/C, EF-Tu domain 2-like domain [141336]
  1. Pseudomonas syringae pv. tomato [TaxId: 323] [141337] (1)
    SQ Q87WW1 238-329
Ribosomal protein L3 [50461] (4)
1. Ribosomal protein L3 [50462]
  superfamily fold is elaborated with additional structures
  1. Archaeon Haloarcula marismortui [TaxId: 2238] [50463] (58)
    SQ P20279
  2. Thermus thermophilus [TaxId: 274] [159158] (11)
    SQ Q72I04 1-205
  3. Escherichia coli [TaxId: 562] [159159] (29)
    SQ P60438 1-209
  4. Deinococcus radiodurans [TaxId: 1299] [159160] (9)
    SQ Q9RXK2 1-205
Ribosomal protein L35ae [117220] (1)
Pfam 01247
1. Ribosomal protein L35ae [117221]
  1. Pyrococcus furiosus [TaxId: 2261] [117222] (1)
    SQ Q8TZV6
RimM N-terminal domain-like [141338] (1)
Pfam 01782
1. 16S rRNA processing protein RimM, N-terminal domain [141339]
  1. Pseudomonas aeruginosa [TaxId: 287] [141340] (1)
    SQ Q9HXQ0 7-95
Gar1-like SnoRNP [141341] (1)
stand alone proteins, which are similar structurally but not sequentially to the elongation factor domains, unlike PF0907
1. Gar1 homolog PF1791 [141342]
  1. Archaeon Pyrococcus furiosus [TaxId: 2261] [141343] (4)
    SQ Q8U029 1-73
AlaX-M N-terminal domain-like [159161] (1)
Does NOT belong to Pfam 01411
1. AlaX-M trans-editing enzyme, N-terminal domain [159162]
  1. Pyrococcus horikoshii [TaxId: 53953] [159163] (1)
    SQ O57848 1-87