Structural Classification of Proteins
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Family: Interleukin-1 (IL-1)

Lineage:

  1. Root: scop
  2. Class: All beta proteins [48724]
  3. Fold: beta-Trefoil [50352]
    barrel, closed; n=6, S=12; and a hairpin triplet; meander
    duplication: has internal pseudo threefold symmetry
  4. Superfamily: Cytokine [50353]
    link to SUPERFAMILY database - Superfamily
  5. Family: Interleukin-1 (IL-1) [50362]

Protein Domains:

  1. Interleukin-1beta [50363]
    1. Human (Homo sapiens) [TaxId: 9606] [50364] (20)
      SQ P01584 117-269
      1. 1l2h picpic
        mutant
        1. chain a [77655] picpiclink
      2. 2nvh picpic
        automatically matched to d1iob__
        complexed with so4
        1. region a:1-152 [138630] picpiclink
      3. 1i1b picpic
        1. chain a [25537] picpiclink
      4. 1too picpic
        mutant
        1. chain a [112604] picpiclink
      5. 1t4q picpic
        mutant
        1. chain a [112244] picpiclink
      6. 1twe picpic
        mutant
        1. chain a [112724] picpiclink
      7. 2i1b picpic
        1. chain a [25538] picpiclink
      8. 5i1b picpic
        1. chain a [25539] picpiclink
      9. 1twm picpic
        mutant
        1. chain a [112765] picpiclink
      10. 9ilb picpic
        1. chain a [25543] picpiclink
      11. 1s0l picpic
        mutant
        1. chain a [98289] picpiclink
      12. 4i1b picpic
        1. chain a [25540] picpiclink
      13. 21bi picpic
        mutant
        1. chain a [25542] picpiclink
      14. 31bi picpic
        mutant
        1. chain a [25541] picpiclink
      15. 1iob picpic
        1. chain a [25547] picpiclink
      16. 1hib picpic
        mutant
        1. chain a [25544] picpiclink
      17. 1itb picpicxref
        1. chain a [25546] picpiclink
      18. 41bi picpic
        mutant
        1. chain a [25545] picpiclink
      19. 7i1b picpic
        1. chain a [25549] picpiclink
      20. 6i1b picpic
        1. chain a [25548] picpiclink
    2. Mouse (Mus musculus) [TaxId: 10090] [50365] (2)
      1. 8i1b picpic
        1. chain a [25550] picpiclink
      2. 2mib picpic
        1. chain a [25551] picpiclink
  2. Interleukin-1 receptor antagonist protein [50366]
    1. Human (Homo sapiens) [TaxId: 9606] [50367] (5)
      1. 1ilr picpic
        1. chain 1 [25552] picpiclink
        2. chain 2 [25553] picpiclink
      2. 1ira picpicxref
        complexed with nag
        1. chain x [25556] picpiclink
      3. 1ilt picpic
        CA-atoms only
        1. chain a [25554] picpiclink
        2. chain b [25555] picpiclink
      4. 1irp picpic
        1. chain a [25559] picpiclink
      5. 2irt picpic
        CA-atoms only
        1. chain a [25557] picpiclink
        2. chain b [25558] picpiclink
  3. Interleukin-1alpha [50368]
    1. Human (Homo sapiens) [TaxId: 9606] [50369] (1)
      1. 2ila picpic
        CA-atoms only
        1. chain a [25560] picpiclink
  4. Interleukin-1F5 [101780]
    1. Mouse (Mus musculus) [TaxId: 10090] [101781] (1)
      1. 1md6 picpic
        1. chain a [91242] picpiclink
  5. Interleukin-18 [101782]
    1. Human (Homo sapiens) [TaxId: 9606] [101783] (1)
      1. 1j0s picpic
        1. chain a [90747] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk