Fold: beta-Trefoil

barrel, closed; n=6, S=12; and a hairpin triplet; meander
duplication: has internal pseudo threefold symmetry

Lineage:

1. Root: scop
2. Class: All beta proteins [48724]
3. Fold: beta-Trefoil [50352]
   barrel, closed; n=6, S=12; and a hairpin triplet; meander
   duplication: has internal pseudo threefold symmetry

Superfamilies:

1. Cytokine [50353] (2)
   uperfamily
   1. Fibroblast growth factors (FGF) [50354] (11)
   2. Interleukin-1 (IL-1) [50362] (6)
2. MIR domain [82109] (1)
   uperfamily
   1. MIR domain [82110] (2)
      Pfam 02815
3. Ricin B-like lectins [50370] (3)
   uperfamily
   1. Ricin B-like [50371] (18)
   2. Cysteine rich domain [50379] (1)
   3. GlcNAc-alpha-1,4-Gal-releasing endo-beta-galactosidase, GngC, C-terminal domain [117212] (1)
4. Agglutinin [50382] (1)
   this superfamily is distinct from the ricin B-like lectin superfamily
   uperfamily
   1. Agglutinin [50383] (1)
5. STI-like [50386] (2)
   uperfamily
   1. Kunitz (STI) inhibitors [50387] (7)
   2. Clostridium neurotoxins, C-terminal domain [50399] (3)
      overall fold is very similar to that of the STI family
6. Actin-crosslinking proteins [50405] (2)
   uperfamily
   1. Fascin [50406] (1)
   2. Histidine-rich actin-binding protein (hisactophilin) [50409] (1)
7. DNA-binding protein LAG-1 (CSL) [110217] (1)
   contains rudiment hairpin triplet lacking one hairpin
   uperfamily
   1. DNA-binding protein LAG-1 (CSL) [110218] (1)
8. AbfB domain [110221] (1)
   uperfamily
   1. AbfB domain [110222] (1)
      Pfam 05270

Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009 Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk