Structural Classification of Proteins

Family: Bacterial AB5 toxins, B-subunits

Lineage:

Root: scop
Class: All beta proteins [48724]
Fold: OB-fold [50198]
barrel, closed or partly opened n=5, S=10 or S=8; greek-key
Superfamily: Bacterial enterotoxins [50203]
uperfamily
Family: Bacterial AB5 toxins, B-subunits [50204]

Protein Domains:

Heat-labile toxin [50205]
1. Escherichia coli, type IB [TaxId: 562] [50206] (29)
  1. 1djr
    complexed with bez, gal, gol
    1. chain d [24865]
    2. chain e [24866]
    3. chain f [24867]
    4. chain g [24868]
    5. chain h [24869]
  2. 1efi
    1. chain d [24870]
    2. chain e [24871]
    3. chain f [24872]
    4. chain g [24873]
    5. chain h [24874]
  3. 1lt5
    complexed with tdg
    1. chain d [24875]
    2. chain e [24876]
    3. chain f [24877]
    4. chain g [24878]
    5. chain h [24879]
  4. 1eef
    1. chain d [24880]
    2. chain e [24881]
    3. chain f [24882]
    4. chain g [24883]
    5. chain h [24884]
    6. chain l [24885]
    7. chain m [24886]
    8. chain n [24887]
    9. chain o [24888]
    10. chain p [24889]
  5. 1fd7
    complexed with ai1
    1. chain d [24890]
    2. chain e [24891]
    3. chain f [24892]
    4. chain g [24893]
    5. chain h [24894]
    6. chain l [24895]
    7. chain m [24896]
    8. chain n [24897]
    9. chain o [24898]
    10. chain p [24899]
  6. 1pzi
    complexed with 1dm
    1. chain d [95441]
    2. chain e [95442]
    3. chain f [95443]
    4. chain g [95444]
    5. chain h [95445]
  7. 1lts
    1. chain d [24900]
    2. chain e [24901]
    3. chain f [24902]
    4. chain g [24903]
    5. chain h [24904]
  8. 1lt3
    complexed with gal, glc; mutant
    1. chain d [24910]
    2. chain e [24911]
    3. chain f [24912]
    4. chain g [24913]
    5. chain h [24914]
  9. 1lt4
    complexed with gal, glc; mutant
    1. chain d [24905]
    2. chain e [24906]
    3. chain f [24907]
    4. chain g [24908]
    5. chain h [24909]
  10. 1lta
    complexed with gal
    1. chain d [24915]
    2. chain e [24916]
    3. chain f [24917]
    4. chain g [24918]
    5. chain h [24919]
  11. 1lti
    complexed with gal, nga
    1. chain d [24920]
    2. chain e [24921]
    3. chain f [24922]
    4. chain g [24923]
    5. chain h [24924]
  12. 1lt6
    complexed with gaa
    1. chain d [24925]
    2. chain e [24926]
    3. chain f [24927]
    4. chain g [24928]
    5. chain h [24929]
    6. chain l [24930]
    7. chain m [24931]
    8. chain n [24932]
    9. chain o [24933]
    10. chain p [24934]
  13. 1ltt
    complexed with gal, glc
    1. chain d [24935]
    2. chain e [24936]
    3. chain f [24937]
    4. chain g [24938]
    5. chain h [24939]
  14. 1jqy
    complexed with a32
    1. chain d [71800]
    2. chain e [71801]
    3. chain f [71802]
    4. chain g [71803]
    5. chain h [71804]
    6. chain l [71805]
    7. chain m [71806]
    8. chain n [71807]
    9. chain o [71808]
    10. chain p [71809]
    11. chain v [71810]
    12. chain w [71811]
    13. chain x [71812]
    14. chain y [71813]
    15. chain z [71814]
  15. 2o2l
    automatically matched to d1ltrf_
    complexed with a2g, bgc, fuc, gal
    1. region d:1-103 [148554]
  16. 2o2l
    automatically matched to d1ltrf_
    complexed with a2g, bgc, fuc, gal
    1. region e:1-103 [148555]
  17. 2o2l
    automatically matched to d1ltrf_
    complexed with a2g, bgc, fuc, gal
    1. region f:1-103 [148556]
  18. 2o2l
    automatically matched to d1ltrf_
    complexed with a2g, bgc, fuc, gal
    1. region g:1-103 [148557]
  19. 2o2l
    automatically matched to d1ltrf_
    complexed with a2g, bgc, fuc, gal
    1. region h:1-103 [148558]
  20. 2o2l
    automatically matched to d1ltrf_
    complexed with a2g, bgc, fuc, gal
    1. region i:1-103 [148559]
  21. 2o2l
    automatically matched to d1ltrf_
    complexed with a2g, bgc, fuc, gal
    1. region j:1-103 [148560]
  22. 2o2l
    automatically matched to d1ltrf_
    complexed with a2g, bgc, fuc, gal
    1. region k:1-103 [148561]
  23. 2o2l
    automatically matched to d1ltrf_
    complexed with a2g, bgc, fuc, gal
    1. region l:1-103 [148562]
  24. 2o2l
    automatically matched to d1ltrf_
    complexed with a2g, bgc, fuc, gal
    1. region m:1-103 [148563]
  25. 1ltg
    mutant
    1. chain d [24940]
    2. chain e [24941]
    3. chain f [24942]
    4. chain g [24943]
    5. chain h [24944]
  26. 1ltb
    1. chain d [24945]
    2. chain e [24946]
    3. chain f [24947]
    4. chain g [24948]
    5. chain h [24949]
  27. 1htl
    mutant
    1. chain d [24950]
    2. chain e [24951]
    3. chain f [24952]
    4. chain g [24953]
    5. chain h [24954]
  28. 1ltr
    extended C-terminally with a peptide with anti-hsv activity
    complexed with so4; mutant
    1. chain d [24955]
    2. chain e [24956]
    3. chain f [24957]
    4. chain g [24958]
    5. chain h [24959]
  29. 1b44
    extended C-terminally with a peptide with anti-hsv activity
    1. chain d [24960]
    2. chain e [24961]
    3. chain f [24962]
    4. chain g [24963]
    5. chain h [24964]
2. Escherichia coli, type IIB [TaxId: 562] [50207] (3)
  1. 1qb5
    1. chain d [88357]
    2. chain e [88358]
    3. chain f [88359]
    4. chain g [88360]
    5. chain h [88361]
  2. 1tii
    1. chain d [24965]
    2. chain e [24966]
    3. chain f [24967]
    4. chain g [24968]
    5. chain h [24969]
  3. 1qcb
    1. chain d [88362]
    2. chain e [88363]
    3. chain f [88364]
    4. chain g [88365]
    5. chain h [88366]
Cholera toxin [50208]
barrel, partly opened; n*=5, S*=10
1. Vibrio cholerae [TaxId: 666] [50209] (33)
  SQ P01556 22-124
  1. 3chb
    complexed with gal, glc, mes, nga, sia, unx; mutant
    1. chain d [24970]
    2. chain e [24971]
    3. chain f [24972]
    4. chain g [24973]
    5. chain h [24974]
  2. 1jr0
    complexed with a24
    1. chain d [71815]
    2. chain e [71816]
    3. chain f [71817]
    4. chain g [71818]
    5. chain h [71819]
  3. 1pzk
    complexed with j12
    1. chain d [95451]
    2. chain e [95452]
    3. chain f [95453]
    4. chain g [95454]
    5. chain h [95455]
  4. 1rf2
    complexed with bv4, pge, tmn
    1. chain d [111790]
    2. chain e [111791]
    3. chain f [111792]
    4. chain g [111793]
    5. chain h [111794]
  5. 1rdp
    complexed with bv3, pge, tmn
    1. chain d [111782]
    2. chain e [111783]
    3. chain f [111784]
    4. chain g [111785]
    5. chain h [111786]
  6. 1pzj
    complexed with 15b, j15
    1. chain d [95446]
    2. chain e [95447]
    3. chain f [95448]
    4. chain g [95449]
    5. chain h [95450]
  7. 1md2
    complexed with 233, s, sq
    1. chain d [79002]
    2. chain e [79003]
    3. chain f [79004]
    4. chain g [79005]
    5. chain h [79006]
  8. 1rd9
    complexed with bv2, p6g, tmn
    1. chain d [111777]
    2. chain e [111778]
    3. chain f [111779]
    4. chain g [111780]
    5. chain h [111781]
  9. 1llr
    complexed with fng, lnq
    1. chain d [74012]
    2. chain e [74013]
    3. chain f [74014]
    4. chain g [74015]
    5. chain h [74016]
  10. 1rcv
    complexed with bv1
    1. chain d [111767]
    2. chain e [111768]
    3. chain f [111769]
    4. chain g [111770]
    5. chain h [111771]
  11. 1s5d
    complexed with gal, gol, na; mutant
    1. chain d [98542]
    2. chain e [98543]
    3. chain f [98544]
    4. chain g [98545]
    5. chain h [98546]
  12. 1s5e
    complexed with gal, na
    1. chain d [98549]
    2. chain e [98550]
    3. chain f [98551]
    4. chain g [98552]
    5. chain h [98553]
    6. chain j [98554]
    7. chain k [98555]
    8. chain l [98556]
    9. chain m [98557]
    10. chain n [98558]
  13. 3efx
    engineered hybrid with E. coli Heat-labile toxin
    complexed with a2g, bgc, fuc, gal
    1. region d:1-102 [158134]
  14. 3efx
    automatically matched to 3EFX D:1-102
    complexed with a2g, bgc, fuc, gal
    1. region e:1-102 [158135]
  15. 3efx
    automatically matched to 3EFX D:1-102
    complexed with a2g, bgc, fuc, gal
    1. region f:1-102 [158136]
  16. 3efx
    automatically matched to 3EFX D:1-102
    complexed with a2g, bgc, fuc, gal
    1. region g:1-102 [158137]
  17. 3efx
    automatically matched to 3EFX D:1-102
    complexed with a2g, bgc, fuc, gal
    1. region h:1-102 [158138]
  18. 3efx
    automatically matched to 3EFX D:1-102
    complexed with a2g, bgc, fuc, gal
    1. region i:1-102 [158139]
  19. 3efx
    automatically matched to 3EFX D:1-102
    complexed with a2g, bgc, fuc, gal
    1. region j:1-102 [158140]
  20. 3efx
    automatically matched to 3EFX D:1-102
    complexed with a2g, bgc, fuc, gal
    1. region k:1-102 [158141]
  21. 3efx
    automatically matched to 3EFX D:1-102
    complexed with a2g, bgc, fuc, gal
    1. region l:1-102 [158142]
  22. 3efx
    automatically matched to 3EFX D:1-102
    complexed with a2g, bgc, fuc, gal
    1. region m:1-102 [158143]
  23. 1g8z
    complexed with gal; mutant
    1. chain d [60383]
    2. chain e [60384]
    3. chain f [60385]
    4. chain g [60386]
    5. chain h [60387]
  24. 2chb
    complexed with gal, glc, nga, sia
    1. chain d [24975]
    2. chain e [24976]
    3. chain f [24977]
    4. chain g [24978]
    5. chain h [24979]
  25. 1eei
    1. chain d [24985]
    2. chain e [24986]
    3. chain f [24987]
    4. chain g [24988]
    5. chain h [24989]
  26. 1chp
    complexed with cl; mutant
    1. chain d [24980]
    2. chain e [24981]
    3. chain f [24982]
    4. chain g [24983]
    5. chain h [24984]
  27. 1s5b
    complexed with na; mutant
    1. chain d [98530]
    2. chain e [98531]
    3. chain f [98532]
    4. chain g [98533]
    5. chain h [98534]
  28. 1ct1
    complexed with cl, gal, glc, nga, sia; mutant
    1. chain d [24990]
    2. chain e [24991]
    3. chain f [24992]
    4. chain g [24993]
    5. chain h [24994]
  29. 1chq
    mutant
    1. chain d [24995]
    2. chain e [24996]
    3. chain f [24997]
    4. chain g [24998]
    5. chain h [24999]
  30. 1s5c
    complexed with na; mutant
    1. chain d [98536]
    2. chain e [98537]
    3. chain f [98538]
    4. chain g [98539]
    5. chain h [98540]
  31. 1s5f
    complexed with gal, na
    1. chain d [98560]
    2. chain e [98561]
    3. chain f [98562]
    4. chain g [98563]
    5. chain h [98564]
  32. 1fgb
    1. chain d [25000]
    2. chain e [25001]
    3. chain f [25002]
    4. chain g [25003]
    5. chain h [25004]
  33. 1xtc
    1. chain d [25005]
    2. chain e [25006]
    3. chain f [25007]
    4. chain g [25008]
    5. chain h [25009]
Verotoxin-1/shiga-toxin, B-pentamer [50210]
phage-borne toxin; bacteriophages H30 and H19B
1. Escherichia coli [TaxId: 562] [50211] (22)
  1. 1c4q
    complexed with gal, glc; mutant
    1. chain a [25010]
    2. chain b [25011]
    3. chain c [25012]
    4. chain d [25013]
    5. chain e [25014]
  2. 1c48
    mutant
    1. chain a [25015]
    2. chain b [25016]
    3. chain c [25017]
    4. chain d [25018]
    5. chain e [25019]
  3. 2bos
    complexed with but, gal, glc; mutant
    1. chain a [25025]
    2. chain b [25026]
    3. chain c [25027]
    4. chain d [25028]
    5. chain e [25029]
  4. 1d1i
    complexed with gal, glc; mutant
    1. chain a [25020]
    2. chain b [25021]
    3. chain c [25022]
    4. chain d [25023]
    5. chain e [25024]
  5. 1d1k
    complexed with gal, glc; mutant
    1. chain a [25030]
    2. chain b [25031]
    3. chain c [25032]
    4. chain d [25033]
    5. chain e [25034]
  6. 1cqf
    complex with Gb3 trisaccharide
    complexed with gal, glc; mutant
    1. chain a [25055]
    2. chain b [25056]
    3. chain c [25057]
    4. chain d [25058]
    5. chain e [25059]
  7. 1czw
    mutant
    1. chain a [25060]
    2. chain b [25061]
    3. chain c [25062]
    4. chain d [25063]
    5. chain e [25064]
    6. chain f [25065]
    7. chain g [25066]
    8. chain h [25067]
    9. chain i [25068]
    10. chain j [25069]
  8. 1bos
    complexed with gal, glc
    1. chain a [25075]
    2. chain b [25076]
    3. chain c [25077]
    4. chain d [25078]
    5. chain e [25079]
    6. chain f [25080]
    7. chain g [25081]
    8. chain h [25082]
    9. chain i [25083]
    10. chain j [25084]
    11. chain k [25085]
    12. chain l [25086]
    13. chain m [25087]
    14. chain n [25088]
    15. chain o [25089]
    16. chain p [25090]
    17. chain q [25091]
    18. chain r [25092]
    19. chain s [25093]
    20. chain t [25094]
  9. 1czg
    mutant
    1. chain a [25095]
    2. chain b [25096]
    3. chain c [25097]
    4. chain d [25098]
    5. chain e [25099]
  10. 1bov
    complexed with zn
    1. chain a [25070]
    2. chain b [25071]
    3. chain c [25072]
    4. chain d [25073]
    5. chain e [25074]
  11. 2c5c
    automatically matched to d1bosa_
    complexed with bgc, gal, gla, glc, s10, so4
    1. region a:1-69 [129902]
  12. 2c5c
    automatically matched to d1bosa_
    complexed with bgc, gal, gla, glc, s10, so4
    1. region b:1-69 [129903]
  13. 2c5c
    automatically matched to d1bosa_
    complexed with bgc, gal, gla, glc, s10, so4
    1. region c:1-69 [129904]
  14. 2c5c
    automatically matched to d1bosa_
    complexed with bgc, gal, gla, glc, s10, so4
    1. region d:1-69 [129905]
  15. 2c5c
    automatically matched to d1bosa_
    complexed with bgc, gal, gla, glc, s10, so4
    1. region e:1-69 [129906]
  16. 2c5c
    automatically matched to d1bosa_
    complexed with bgc, gal, gla, glc, s10, so4
    1. region f:1-69 [129907]
  17. 2c5c
    automatically matched to d1bosa_
    complexed with bgc, gal, gla, glc, s10, so4
    1. region g:1-69 [129908]
  18. 2c5c
    automatically matched to d1bosa_
    complexed with bgc, gal, gla, glc, s10, so4
    1. region h:1-69 [129909]
  19. 2c5c
    automatically matched to d1bosa_
    complexed with bgc, gal, gla, glc, s10, so4
    1. region i:1-69 [129910]
  20. 2c5c
    automatically matched to d1bosa_
    complexed with bgc, gal, gla, glc, s10, so4
    1. region j:1-69 [129911]
  21. 4ull
    1. chain a [25100]
  22. 1qoh
    A mutant shiga-like toxin IIe
    1. chain a [25035]
    2. chain b [25036]
    3. chain c [25037]
    4. chain d [25038]
    5. chain e [25039]
    6. chain f [25040]
    7. chain g [25041]
    8. chain h [25042]
    9. chain i [25043]
    10. chain j [25044]
    11. chain k [25045]
    12. chain l [25046]
    13. chain m [25047]
    14. chain n [25048]
    15. chain o [25049]
    16. chain p [25050]
    17. chain q [25051]
    18. chain r [25052]
    19. chain s [25053]
    20. chain t [25054]
2. Shigella dysenteriae, toxin I [TaxId: 622] [50212] (3)
  identical sequence with verotoxin-1 B
  1. 1qnu
    complexed with emb, gal, glc, mec
    1. chain a [25101]
    2. chain b [25102]
    3. chain c [25103]
    4. chain d [25104]
    5. chain e [25105]
  2. 1r4q
    1. chain b [97032]
    2. chain c [97033]
    3. chain d [97034]
    4. chain e [97035]
    5. chain f [97036]
    6. chain g [97037]
    7. chain h [97038]
    8. chain i [97039]
    9. chain j [97040]
    10. chain k [97041]
  3. 1dm0
    1. chain b [25106]
    2. chain c [25107]
    3. chain d [25108]
    4. chain e [25109]
    5. chain f [25110]
    6. chain g [25111]
    7. chain h [25112]
    8. chain i [25113]
    9. chain j [25114]
    10. chain k [25115]
3. Shigella dysenteriae, toxin II [TaxId: 622] [101755] (6)
  1. 1r4p
    complexed with 1ps, edo, fmt, na
    1. chain b [97026]
    2. chain c [97027]
    3. chain d [97028]
    4. chain e [97029]
    5. chain f [97030]
  2. 2ga4
    automatically matched to d1r4pb_
    complexed with 1ps, ade, edo, fmt, na
    1. region b:1-70 [134855]
  3. 2ga4
    automatically matched to d1r4pb_
    complexed with 1ps, ade, edo, fmt, na
    1. region c:1-70 [134856]
  4. 2ga4
    automatically matched to d1r4pb_
    complexed with 1ps, ade, edo, fmt, na
    1. region d:1-70 [134857]
  5. 2ga4
    automatically matched to d1r4pb_
    complexed with 1ps, ade, edo, fmt, na
    1. region e:1-70 [134858]
  6. 2ga4
    automatically matched to d1r4pb_
    complexed with 1ps, ade, edo, fmt, na
    1. region f:1-70 [134859]
Pertussis toxin S2/S3 subunits, C-terminal domain [50213]
N-terminal domain in S2/S3 has C-lectin-like fold
1. Bordetella pertussis [TaxId: 520] [50214] (3)
  1. 1prt
    1. region b:90-199 [25116]
    2. region c:90-199 [25117]
    3. region h:90-199 [25118]
    4. region i:90-199 [25119]
  2. 1bcp
    complexed with atp
    1. region b:90-199 [25120]
    2. region c:90-199 [25121]
    3. region h:90-199 [25122]
    4. region i:90-199 [25123]
  3. 1pto
    complexed with gal, sia
    1. region b:90-199 [25124]
    2. region c:90-199 [25125]
    3. region h:90-199 [25126]
    4. region i:90-199 [25127]
Pertussis toxin S4 subunit [50215]
1. Bordetella pertussis [TaxId: 520] [50216] (3)
  1. 1prt
    1. chain d [25128]
    2. chain e [25129]
    3. chain j [25130]
    4. chain k [25131]
  2. 1bcp
    complexed with atp
    1. chain d [25132]
    2. chain e [25133]
    3. chain j [25134]
    4. chain k [25135]
  3. 1pto
    complexed with gal, sia
    1. chain d [25136]
    2. chain e [25137]
    3. chain j [25138]
    4. chain k [25139]
Pertussis toxin S5 subunit [50217]
1. Bordetella pertussis [TaxId: 520] [50218] (3)
  1. 1prt
    1. chain f [25140]
    2. chain l [25141]
  2. 1bcp
    complexed with atp
    1. chain f [25142]
    2. chain l [25143]
  3. 1pto
    complexed with gal, sia
    1. chain f [25144]
    2. chain l [25145]