Structural Classification of Proteins
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Superfamily: Tudor/PWWP/MBT

link to SUPERFAMILY database - Superfamily

Lineage:

  1. Root: scop
  2. Class: All beta proteins [48724]
  3. Fold: SH3-like barrel [50036]
    barrel, partly opened; n*=4, S*=8; meander
    the last strand is interrupted by a turn of 3-10 helix
  4. Superfamily: Tudor/PWWP/MBT [63748]
    link to SUPERFAMILY database - Superfamily

Families:

  1. Tudor domain [63749] (7)
    Pfam 00567
    1. Survival motor neuron protein 1, smn [63750]
      1. Human (Homo sapiens) [TaxId: 9606] [63751] (2) picpic
    2. p53-binding protein 1, 53BP1 [110163]
      duplication; contains two Tudor domains in tandem
      1. Human (Homo sapiens) [TaxId: 9606] [110164] (6) picpic
        SQ Q12888 1485-1602 ! SQ Q12888 1484-1606
    3. Tudor domain-containing protein 3, TDRD3 [141201]
      1. Mouse (Mus musculus) [TaxId: 10090] [141202] (1) picpic
        SQ Q91W18 553-612
    4. Jumonji domain-containing protein 2A [141203]
      contains tandem repeat of two segment-swapped Tudor domains
      1. Human (Homo sapiens) [TaxId: 9606] [141204] (20) picpic
        SQ O75164 897-955! SQ O75164 956-1011
    5. Tudor and KH domain-containing protein TDRKH [141205]
      1. Human (Homo sapiens) [TaxId: 9606] [141206] (1) picpic
        SQ Q9Y2W6 329-425
    6. P100 co-activator, SND1 [141207]
      1. Human (Homo sapiens) [TaxId: 9606] [141208] (2) picpic
        SQ Q7KZF4 705-794
    7. Lamin-b receptor [141209]
      1. Human (Homo sapiens) [TaxId: 9606] [141210] (1) picpic
        SQ Q14739 1-55
  2. PWWP domain [69250] (6)
    includes the C-terminal all-alpha subdomain
    1. DNA methyltransferase DNMT3B [69251]
      1. Mouse (Mus musculus) [TaxId: 10090] [69252] (1) picpic
    2. Hypothetical protein SPBC215.07c [89297]
      1. Fission yeast (Schizosaccharomyces pombe) [TaxId: 4896] [89298] (1) picpic
    3. Hepatoma-derived growth factor, related protein 3 [101684]
      1. Mouse (Mus musculus) [TaxId: 10090] [101685] (1) picpic
    4. Hepatoma-derived growth factor, HDGF [117151]
      1. Human (Homo sapiens) [TaxId: 9606] [117152] (3) picpic
        SQ P51858 1-100
      2. Rat (Rattus norvegicus) [TaxId: 10116] [141211] (1) picpic
        SQ Q8VHK7 1-110
    5. Histone-lysine N-methyltransferase NSD3 [141212]
      WHSC1L1
      1. Human (Homo sapiens) [TaxId: 9606] [141213] (1) picpic
        SQ Q9BZ95 957-1053
  3. MBT repeat [89299] (4)
    Pfam 02820
    contains extended 'arm', N-terminal to the common fold core
    1. Scml2 protein [89300]
      duplication: contains tandem repeat of two MBT repeats
      1. Human (Homo sapiens) [TaxId: 9606] [89301] (7) picpic
    2. Lethal(3)malignant brain tumor-like protein [101686]
      1. Human (Homo sapiens) [TaxId: 9606] [101687] (3) picpic
    3. Lethal(3)malignant brain tumor-like 3 protein, L3MBTL3 (KIAA1798) [117153]
      1. Human (Homo sapiens) [TaxId: 9606] [117154] (2) picpic
        SQ Q96JM7 259-372, 469-562
    4. Scm-like with four MBT domains protein 2, SFMBT2 (KIAA1617) [117155]
      1. Human (Homo sapiens) [TaxId: 9606] [117156] (1) picpic
        SQ Q5VUG0 181-285
  4. CPH domain [159021] (1)
    1. Cullin-7 [159022]
      1. Human (Homo sapiens) [TaxId: 9606] [159023] (1) picpic
        SQ Q14999 360-435
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk