Structural Classification of Proteins
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Family: SMAD domain

Lineage:

  1. Root: scop
  2. Class: All beta proteins [48724]
  3. Fold: SMAD/FHA domain [49878]
    sandwich; 11 strands in 2 sheets; greek-key
  4. Superfamily: SMAD/FHA domain [49879]
    has a few short helices inserted in loops
    link to SUPERFAMILY database - Superfamily
  5. Family: SMAD domain [49880]

Protein Domains:

  1. Smad4 tumor suppressor C-terminal domain [49881]
    1. Human (Homo sapiens) [TaxId: 9606] [49882] (6)
      SQ Q13485 314-546
      1. 1ygs picpic
        1. chain a [23907] picpiclink
      2. 1dd1 picpic
        1. chain a [23908] picpiclink
        2. chain b [23909] picpiclink
        3. chain c [23910] picpiclink
      3. 1g88 picpic
        mutant
        1. chain a [23911] picpiclink
        2. chain b [23912] picpiclink
        3. chain c [23913] picpiclink
      4. 1u7f picpicxref
        1. chain b [107721] picpiclink
      5. 1u7v picpicxref
        1. chain b [107730] picpiclink
      6. 1mr1 picpicxref
        complex with Ski
        complexed with zn
        1. chain a [79418] picpiclink
        2. chain b [79419] picpiclink
  2. Smad3 MH2 domain [82030]
    1. Human (Homo sapiens) [TaxId: 9606] [82031] (4)
      SQ P84022 228-425
      1. 1mjs picpic
        1. chain a [79211] picpiclink
      2. 1u7f picpicxref
        1. chain a [107720] picpiclink
        2. chain c [107722] picpiclink
      3. 1u7v picpicxref
        1. chain a [107729] picpiclink
        2. chain c [107731] picpiclink
      4. 1mk2 picpicxref
        complexed with acy
        1. chain a [79217] picpiclink
  3. Smad2 MH2 domain [49883]
    1. Human (Homo sapiens) [TaxId: 9606] [49884] (2)
      1. 1khx picpic
        1. chain a [68631] picpiclink
      2. 1dev picpicxref
        1. chain a [23914] picpiclink
        2. chain c [23915] picpiclink
  4. Smad1 [69233]
    1. Human (Homo sapiens) [TaxId: 9606] [69234] (1)
      1. 1khu picpic
        1. chain a [68623] picpiclink
        2. chain b [68624] picpiclink
        3. chain c [68625] picpiclink
        4. chain d [68626] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk