Structural Classification of Proteins
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Family: RUNT domain

Lineage:

  1. Root: scop
  2. Class: All beta proteins [48724]
  3. Fold: Common fold of diphtheria toxin/transcription factors/cytochrome f [49379]
    sandwich; 9 strands in 2 sheet; greek-key; subclass of immunoglobin-like fold
  4. Superfamily: p53-like transcription factors [49417]
    link to SUPERFAMILY database - Superfamily
  5. Family: RUNT domain [81318]

Protein Domains:

  1. Acute myeloid leukemia 1 protein (AML1), RUNT domain [49439]
    synonym: core binding factor alpha, cbfa
    1. Human (Homo sapiens) [TaxId: 9606] [49440] (5)
      1. 1ljm picpic
        complexed with cl
        1. chain a [78051] picpiclink
        2. chain b [78052] picpiclink
      2. 1e50 picpicxref
        1. chain a [59244] picpiclink
        2. chain c [59246] picpiclink
        3. chain e [59248] picpiclink
        4. chain g [59250] picpiclink
        5. chain q [59252] picpiclink
        6. chain r [59253] picpiclink
      3. 1h9d picpicxref
        1. chain a [60821] picpiclink
        2. chain c [60823] picpiclink
      4. 1cmo picpic
        1. chain a [22462] picpiclink
      5. 1co1 picpic
        1. chain a [22463] picpiclink
    2. Mouse (Mus musculus) [TaxId: 10090] [63684] (6)
      almost identical sequence to the human protein
      1. 1eaq picpic
        complexed with cl, mse; mutant
        1. chain a [76144] picpiclink
        2. chain b [76145] picpiclink
      2. 1eao picpic
        complexed with br; mutant
        1. chain a [76142] picpiclink
        2. chain b [76143] picpiclink
      3. 1ean picpic
        complexed with cl; mutant
        1. chain a [76141] picpiclink
      4. 1hjc picpic
        1. chain a [61079] picpiclink
        2. chain d [61080] picpiclink
      5. 1hjb picpicxref
        1. chain c [61075] picpiclink
        2. chain f [61078] picpiclink
      6. 1io4 picpicxrefxref
        complexed with au
        1. chain c [62616] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk