Structural Classification of Proteins
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Family: Rel/Dorsal transcription factors, DNA-binding domain

Lineage:

  1. Root: scop
  2. Class: All beta proteins [48724]
  3. Fold: Common fold of diphtheria toxin/transcription factors/cytochrome f [49379]
    sandwich; 9 strands in 2 sheet; greek-key; subclass of immunoglobin-like fold
  4. Superfamily: p53-like transcription factors [49417]
    link to SUPERFAMILY database - Superfamily
  5. Family: Rel/Dorsal transcription factors, DNA-binding domain [81315]

Protein Domains:

  1. T-cell transcription factor NFAT1 (NFATC), DNA-binding domain [49421]
    1. Human (Homo sapiens) [TaxId: 9606] [49422] (12)
      1. 1p7h picpicxref
        1. region l:393-575 [94272] picpiclink
        2. region m:393-575 [94274] picpiclink
        3. region n:393-575 [94276] picpiclink
        4. region o:393-575 [94278] picpiclink
      2. 2as5 picpicxrefxrefxrefxref
        automatically matched to d1p7hl2
        complexed with mg; mutant
        1. region m:396-575 [127238] picpiclink
      3. 2as5 picpicxrefxrefxrefxref
        automatically matched to d1p7hl2
        complexed with mg; mutant
        1. region n:396-575 [127240] picpiclink
      4. 2o93 picpicxrefxrefxref
        automatically matched to d1p7hl2
        1. region l:393-575 [138944] picpiclink
      5. 2o93 picpicxrefxrefxref
        automatically matched to d1p7hl2
        1. region m:395-575 [138946] picpiclink
      6. 2o93 picpicxrefxrefxref
        automatically matched to d1p7hl2
        1. region o:393-575 [138948] picpiclink
      7. 1owr picpicxref
        1. region m:395-575 [93658] picpiclink
        2. region n:395-575 [93660] picpiclink
        3. region p:395-575 [93662] picpiclink
        4. region q:395-575 [93664] picpiclink
      8. 1a02 picpicxrefxrefxref
        mutant
        1. region n:399-576 [22440] picpiclink
      9. 1s9k picpicxrefxrefxref
        automatically matched to d1p7hl2
        1. region c:399-575 [118922] picpiclink
      10. 1pzu picpicxref
        1. region b:399-571 [95472] picpiclink
        2. region d:399-571 [95474] picpiclink
        3. region h:399-571 [95476] picpiclink
        4. region i:399-571 [95478] picpiclink
        5. region l:399-571 [95480] picpiclink
        6. region m:399-571 [95482] picpiclink
      11. 1a66 picpic
        protein/DNA complex; mutant
        1. chain a [22441] picpiclink
      12. 1nfa picpic
        1. chain a [22442] picpiclink
  2. T-cell transcription factor NFAT5 (TONEBP), DNA-binding domain [69185]
    1. Human (Homo sapiens) [TaxId: 9606] [69186] (1)
      1. 1imh picpicxref
        1. region c:188-367 [66215] picpiclink
        2. region d:188-367 [66217] picpiclink
  3. p50 subunit of NF-kappa B (NFKB), N-terminal domain [49423]
    1. Human (Homo sapiens) [TaxId: 9606] [49424] (2)
      1. 1svc picpicxref
        protein/DNA complex; mutant
        1. region p:43-250 [22443] picpiclink
      2. 2o61 picpicxref
        automatically matched to d1svcp2
        1. region b:40-246 [148621] picpiclink
    2. Mouse (Mus musculus) [TaxId: 10090] [49425] (8)
      1. 1ooa picpicxref
        1. region a:38-250 [87193] picpiclink
        2. region b:38-250 [87195] picpiclink
      2. 1nfk picpicxref
        protein/DNA complex
        1. region a:39-250 [22444] picpiclink
        2. region b:39-250 [22445] picpiclink
      3. 2i9t picpicxrefxrefxref
        automatically matched to d1le5b2
        1. region b:339-547 [137132] picpiclink
      4. 1lei picpicxrefxrefxref
        complexed with 5it
        1. region b:39-250 [84602] picpiclink
      5. 1le5 picpicxrefxrefxref
        1. region b:38-250 [84586] picpiclink
        2. region f:38-250 [84590] picpiclink
      6. 1vkx picpicxrefxrefxref
        protein/DNA complex
        1. region b:339-546 [22446] picpiclink
      7. 2v2t picpicxref
        automatically matched to d1le5b2
        1. region b:39-247 [152426] picpiclink
      8. 1le9 picpicxrefxrefxref
        1. region b:39-250 [84594] picpiclink
        2. region f:39-250 [84598] picpiclink
  4. p52 subunit of NF-kappa B (NFKB), N-terminal domain [49426]
    1. Human (Homo sapiens) [TaxId: 9606] [49427] (1)
      1. 1a3q picpicxref
        protein/DNA complex; mutant
        1. region a:37-226 [22447] picpiclink
        2. region b:37-226 [22448] picpiclink
  5. p65 subunit of NF-kappa B (NFKB), N-terminal domain [49428]
    1. Mouse (Mus musculus) [TaxId: 10090] [49429] (8)
      1. 2ram picpicxref
        protein/DNA complex; complexed with 5iu, dtt
        1. region a:19-191 [22450] picpiclink
        2. region b:19-191 [22451] picpiclink
      2. 1ikn picpicxrefxrefxref
        1. region a:19-191 [22449] picpiclink
      3. 2i9t picpicxrefxrefxref
        automatically matched to d1le5a2
        1. region a:20-190 [137130] picpiclink
      4. 1lei picpicxrefxrefxref
        complexed with 5it
        1. region a:19-191 [84600] picpiclink
      5. 1ram picpicxref
        protein/DNA complex; complexed with dtt
        1. region a:19-191 [22452] picpiclink
        2. region b:19-191 [22453] picpiclink
      6. 1le5 picpicxrefxrefxref
        1. region a:18-191 [84584] picpiclink
        2. region e:18-191 [84588] picpiclink
      7. 1vkx picpicxrefxrefxref
        protein/DNA complex
        1. region a:19-191 [22454] picpiclink
      8. 1le9 picpicxrefxrefxref
        1. region a:19-191 [84592] picpiclink
        2. region e:19-191 [84596] picpiclink
    2. Human (Homo sapiens) [TaxId: 9606] [49430] (1)
      1. 1nfi picpicxrefxrefxref
        1. region a:20-189 [22455] picpiclink
        2. region c:20-189 [22456] picpiclink
    3. Chicken (Gallus gallus), C-rel [TaxId: 9031] [74867] (1)
      1. 1gji picpicxref
        1. region a:7-181 [70188] picpiclink
        2. region b:7-181 [70190] picpiclink
  6. Dorsal homologue Gambif1 [49431]
    1. African malaria mosquito (Anopheles gambiae) [TaxId: 7165] [49432] (1)
      1. 1bvo picpic
        protein/DNA complex
        1. chain a [22457] picpiclink

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MRC
site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk