Structural Classification of Proteins

Fold: Composite domain of metallo-dependent hydrolases

: pseudobarrel; mixed sheet of 7 strand folded upon itself and "buckled" by two beta-turns

Lineage:

Root: scop
Class: All beta proteins [48724]
Fold: Composite domain of metallo-dependent hydrolases [51337]
pseudobarrel; mixed sheet of 7 strand folded upon itself and "buckled" by two beta-turns

Superfamilies:

Composite domain of metallo-dependent hydrolases [51338] (11)
this domain is interrupted by the catalytic beta/alpha barrel domain
uperfamily
1. Cytosine deaminase [69373] (1)
  1. Cytosine deaminase [69374]
    1. Escherichia coli [TaxId: 562] [69375] (8)
      SQ P25524
2. alpha-Subunit of urease [51339] (3)
  1. alpha-Subunit of urease [51340]
    1. Klebsiella aerogenes [TaxId: 28451] [51341] (27)
    2. Bacillus pasteurii [TaxId: 1474] [51342] (6)
    3. Helicobacter pylori [TaxId: 210] [69376] (2)
3. Hydantoinase (dihydropyrimidinase) [75044] (9)
  1. D-hydantoinase [75045]
    1. Thermus sp. [TaxId: 275] [75046] (2)
    2. Bacillus stearothermophilus [TaxId: 1422] [75047] (1)
    3. Burkholderia pickettii [TaxId: 329] [89437] (1)
    4. Bacillus sp. AR9 [TaxId: 301298] [141682] (2)
      SQ Q5DLU2 2-52,385-460
  2. L-hydantoinase [75048]
    1. Arthrobacter aurescens [TaxId: 43663] [75049] (1)
  3. Dihydropyrimidinase related protein-1 [102017]
    1. Mouse (Mus musculus) [TaxId: 10090] [102018] (1)
  4. Dihydropyrimidine amidohydrolase Pyd2 [141683]
    1. Yeast (Saccharomyces kluyveri) [TaxId: 4934] [141684] (12)
      SQ Q9P903 2-56,441-541
    2. Dictyostelium discoideum [TaxId: 44689] [141685] (1)
      SQ Q86LT2 7-59,394-490
  5. Two-domain dihydroorotase [141686]
    1. Aquifex aeolicus [TaxId: 63363] [141687] (3)
      SQ O66990 1-55,366-422
4. SAH/MTA deaminase-like [82224] (5)
  1. Hypothetical protein TM0936 [82225]
    1. Thermotoga maritima [TaxId: 2336] [82226] (3)
  2. Hypothetical protein GOS_1943094 [159334]
    1. Environmental samples [159335] (1)
  3. Guanine deaminase [159336]
    1. Bradyrhizobium japonicum [TaxId: 375] [159337] (1)
      SQ Q89NG0 1-70,396-465
      Blr3880
    2. Human (Homo sapiens) [TaxId: 9606] [159338] (1)
      SQ Q9Y2T3 8-75,389-451
    3. Clostridium acetobutylicum [TaxId: 1488] [159339] (2)
      SQ Q97MB6 6-63,374-424
5. Isoaspartyl dipeptidase [89438] (1)
  1. Isoaspartyl dipeptidase [89439]
    1. Escherichia coli [TaxId: 562] [89440] (5)
      SQ P39377
6. N-acetylglucosamine-6-phosphate deacetylase, NagA [82227] (3)
  1. N-acetylglucosamine-6-phosphate deacetylase, NagA [82228]
    1. Bacillus subtilis [TaxId: 1423] [102019] (1)
    2. Thermotoga maritima [TaxId: 2336] [82229] (1)
      TM0814
    3. Escherichia coli [TaxId: 562] [141688] (10)
      SQ P0AF18 1-53,351-382
7. D-aminoacylase [82230] (1)
  1. N-acyl-D-aminoacid amidohydrolase [82231]
    1. Alcaligenes faecalis [TaxId: 511] [82232] (8)
8. Adenine deaminase [141689] (1)
  1. Putative adenine deaminase EF0837 [141690]
    1. Enterococcus faecalis [TaxId: 1351] [141691] (1)
      SQ Q837K0 2-52,320-369
9. Zn-dependent arginine carboxypeptidase-like [159340] (3)
  1. Uncharacterized protein EAJ56179 [159341]
    1. Unidentified organism [TaxId: 32644] [159342] (8)
      94% identity to the Burkholderia phytofirmans ortholog Bphyt_2089 (SQ B2T4I1)
  2. Zn-dependent arginine carboxypeptidase [159343]
    1. Unidentified organism [TaxId: 32644] [159344] (16)
  3. Xaa-Pro dipeptidase [159345]
    1. Alteromonas macleodii [TaxId: 28108] [159346] (2)
10. Imidazolonepropionase-like [159347] (4)
  1. Imidazolonepropionase [159348]
    1. Bacillus subtilis [TaxId: 1423] [159349] (4)
      SQ P42084 3-73,374-415
    2. Agrobacterium tumefaciens [TaxId: 358] [159350] (4)
      SQ Q8U8Z6 15-77,379-418
  2. Probable 4-imidazolone-5-propanoate amidohydrolase GOS_1928421 [159351]
    1. Environmental samples [159352] (2)
      marine metagenome
  3. Uncharacterized protein BL1453 [159353]
    1. Bifidobacterium longum [TaxId: 216816] [159354] (1)
      SQ Q8G4D5 7-68,393-448
11. DR0824-like [159355] (1)
  1. Hypothetical protein DR0824 [159356]
    1. Deinococcus radiodurans [TaxId: 1299] [159357] (1)
      SQ Q9RW45 34-90,399-418