Structural Classification of Proteins
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Family: Penicillin synthase-like

common fold is rather distorted

Lineage:

  1. Root: scop
  2. Class: All beta proteins [48724]
  3. Fold: Double-stranded beta-helix [51181]
    one turn of helix is made by two pairs of antiparallel strands linked with short turns
    has appearance of a sandwich of distinct architecture and jelly-roll topology
  4. Superfamily: Clavaminate synthase-like [51197]
    Iron and ketoglutarate-dependent enzymes; elaborated version of this common fold
    link to SUPERFAMILY database - Superfamily
  5. Family: Penicillin synthase-like [51198]
    common fold is rather distorted

Protein Domains:

  1. Isopenicillin N synthase [51199]
    1. Emericella nidulans [TaxId: 162425] [51200] (29)
      SQ P05326
      1. 1odm picpic
        complexed with asv, fe2, so4
        1. chain a [86875] picpiclink
      2. 2ivi picpic
        automatically matched to d1bk0__
        complexed with acw, fe2, so4
        1. region b:3-331 [137723] picpiclink
      3. 2bjs picpic
        automatically matched to d1bk0__
        complexed with acv, fe, mee, so4; mutant
        1. region a:3-322 [128632] picpiclink
      4. 2bu9 picpic
        automatically matched to d1bk0__
        complexed with fe, hfv, so4
        1. region a:3-331 [129169] picpiclink
      5. 2jb4 picpic
        automatically matched to d1bk0a_
        complexed with a14, fe, gol, so4
        1. region a:3-331 [147954] picpiclink
      6. 1qje picpic
        Ip1 - Fe complex
        complexed with acv, fe2, ip1, so4
        1. chain a [28117] picpiclink
      7. 1w04 picpic
        automatically matched to d1bk0__
        complexed with fe2, hcg, no, so4
        1. region a:3-331 [120557] picpiclink
      8. 1bk0 picpic
        complexed with acv, fe, so4
        1. chain a [28118] picpiclink
      9. 1uzw picpic
        complexed with cdh, fe2, so4
        1. chain a [108183] picpiclink
      10. 1hb2 picpic
        complexed with fe2, scv, so4
        1. chain a [65749] picpiclink
      11. 1obn picpic
        complexed with asv, fe2, nmo, so4
        1. chain a [92763] picpiclink
      12. 1qjf picpic
        monocyclic sulfoxide - Fe complex
        complexed with acs, fe2, so4
        1. chain a [28119] picpiclink
      13. 2vbb picpic
        automatically matched to d1bk0a_
        complexed with fe2, gol, so4, vaz
        1. region a:3-331 [152905] picpiclink
      14. 1w3v picpic
        automatically matched to d1bk0__
        complexed with fe2, mdz
        1. region a:3-331 [120624] picpiclink
      15. 2ivj picpic
        automatically matched to d1bk0__
        complexed with bcv, fe2, so4
        1. region a:3-331 [137724] picpiclink
      16. 1hb3 picpic
        complexed with fe2, scv, so4
        1. chain a [65750] picpiclink
      17. 1w3x picpic
        automatically matched to d1bk0__
        complexed with fe2, w2x
        1. region a:3-331 [120625] picpiclink
      18. 1blz picpic
        complexed with acv, fe, no
        1. chain a [28120] picpiclink
      19. 1qiq picpic
        complexed with acc, fe, so4
        1. chain a [28121] picpiclink
      20. 1hb4 picpic
        complexed with fe2, scv, so4
        1. chain a [65751] picpiclink
      21. 1odn picpic
        complexed with apv, fe2, so4
        1. chain a [86876] picpiclink
      22. 1hb1 picpic
        complexed with fe2, ocv, so4
        1. chain a [65748] picpiclink
      23. 1w06 picpic
        automatically matched to d1bk0__
        complexed with fe2, no, so4, w05
        1. region a:3-331 [120559] picpiclink
      24. 2vau picpic
        automatically matched to d1bk0a_
        complexed with fe2, v20
        1. region a:3-331 [152843] picpiclink
      25. 2vbd picpic
        automatically matched to d1bk0a_
        complexed with fe2, v10
        1. region a:3-331 [152906] picpiclink
      26. 1w03 picpic
        automatically matched to d1bk0__
        complexed with fe2, hcg, so4
        1. region a:3-331 [120556] picpiclink
      27. 1oc1 picpic
        complexed with asv, fe2, so4
        1. chain a [92764] picpiclink
      28. 1w05 picpic
        automatically matched to d1bk0__
        complexed with fe2, so4, w05
        1. region a:3-331 [120558] picpiclink
      29. 1ips picpic
        complexed with mn
        1. chain a [28122] picpiclink
        2. chain b [28123] picpiclink
  2. Deacetoxycephalosporin C synthase [51201]
    1. Streptomyces clavuligerus [TaxId: 1901] [51202] (17)
      SQ P18548
      1. 1dcs picpic
        complexed with so4
        1. chain a [28124] picpiclink
      2. 1rxg picpic
        complexed with akg, fe, so4
        1. chain a [28125] picpiclink
      3. 1rxf picpic
        complexed with fe
        1. chain a [28126] picpiclink
      4. 1uo9 picpic
        complexed with fe2, sin
        1. chain a [99684] picpiclink
      5. 1unb picpic
        complexed with akg, fe2, pn1
        1. chain a [99673] picpiclink
      6. 1hjg picpic
        complexed with fe2, kiv; mutant
        1. chain a [61082] picpiclink
      7. 2jb8 picpic
        automatically matched to d1dcsa_
        complexed with fe, hkv
        1. region a:1-308 [147961] picpiclink
      8. 1uof picpic
        complexed with fe2, pnn
        1. chain a [99688] picpiclink
      9. 1hjf picpic
        complexed with coi, fe2; mutant
        1. chain a [61081] picpiclink
      10. 1uob picpic
        complexed with akg, fe2, pnn
        1. chain a [99685] picpiclink
      11. 1uog picpic
        complexed with fe2, p1c
        1. chain a [99689] picpiclink
      12. 1e5h picpic
        complexed with co2, fe2, sin; mutant
        1. chain a [59269] picpiclink
      13. 1w28 picpic
        1. chain a [114098] picpiclink
      14. 1e5i picpic
        complexed with akg, fe2; mutant
        1. chain a [59270] picpiclink
      15. 1w2a picpic
        complexed with edo, fe
        1. chain x [114099] picpiclink
      16. 1w2n picpic
        complexed with fe, pn1
        1. chain a [114100] picpiclink
      17. 1w2o picpic
        complexed with fe, p1c
        1. chain a [114101] picpiclink
  3. Anthocyanidin synthase [69346]
    1. Mouse-ear cress (Arabidopsis thaliana) [TaxId: 3702] [69347] (4)
      1. 1gp6 picpic
        complexed with dh2, fe2, mes, que, sin
        1. chain a [65441] picpiclink
      2. 1gp4 picpic
        complexed with 2og, mes
        1. chain a [65439] picpiclink
      3. 1gp5 picpic
        complexed with 2og, dh2, dqh, fe, mes
        1. chain a [65440] picpiclink
      4. 2brt picpic
        automatically matched to d1gp6a_
        complexed with akg, fe2, nar
        1. region a:2-349 [129018] picpiclink
  4. 1-aminocyclopropane-1-carboxylate oxidase 1 [141621]
    1. Petunia hybrida [TaxId: 4102] [141622] (2)
      SQ Q08506 2-308
      1. 1w9y picpic
        complexed with so4
        1. region a:2-308 [120801] picpiclink
      2. 1wa6 picpic
        automatically matched to 1W9Y A:2-308
        complexed with fe2, po4, so4
        1. region x:2-307 [120808] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk