Structural Classification of Proteins
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Family: PLC-like (P variant)

Lineage:

  1. Root: scop
  2. Class: All beta proteins [48724]
  3. Fold: C2 domain-like [49561]
    sandwich; 8 strands in 2 sheets; greek-key
  4. Superfamily: C2 domain (Calcium/lipid-binding domain, CaLB) [49562]
    two constituent families are related by circular permutation
    link to SUPERFAMILY database - Superfamily
  5. Family: PLC-like (P variant) [49563]

Protein Domains:

  1. PI-specific phospholipase C isozyme D1 (PLC-D1), C-terminal domain [49564]
    1. Rat (Rattus norvegicus) [TaxId: 10116] [49565] (10)
      1. 1qas picpicxrefxref
        1. region a:626-756 [23157] picpiclink
        2. region b:626-756 [23158] picpiclink
      2. 1djx picpicxrefxref
        complexed with act, ca, i3p; mutant
        1. region a:626-756 [23159] picpiclink
        2. region b:626-756 [23160] picpiclink
      3. 1djh picpicxrefxref
        complexed with act, ba; mutant
        1. region a:626-756 [23163] picpiclink
        2. region b:626-756 [23164] picpiclink
      4. 1djw picpicxrefxref
        complexed with act, ca, cip; mutant
        1. region a:626-756 [23161] picpiclink
        2. region b:626-756 [23162] picpiclink
      5. 1dji picpicxrefxref
        complexed with act, ca; mutant
        1. region a:626-756 [23165] picpiclink
        2. region b:626-756 [23166] picpiclink
      6. 1djg picpicxrefxref
        complexed with act, la; mutant
        1. region a:626-756 [23167] picpiclink
        2. region b:626-756 [23168] picpiclink
      7. 2isd picpicxrefxref
        complexed with act; mutant
        1. region a:626-756 [23169] picpiclink
        2. region b:626-756 [23170] picpiclink
      8. 1djy picpicxrefxref
        complexed with act, ca, i2p; mutant
        1. region a:626-756 [23173] picpiclink
        2. region b:626-756 [23174] picpiclink
      9. 1djz picpicxrefxref
        complexed with act, ca, ip2; mutant
        1. region a:626-756 [23175] picpiclink
        2. region b:626-756 [23176] picpiclink
      10. 1qat picpicxrefxref
        complexed with sm
        1. region a:626-756 [23171] picpiclink
        2. region b:626-756 [23172] picpiclink
  2. Domain from cytosolic phospholipase A2 [49566]
    1. Human (Homo sapiens) [TaxId: 9606] [49567] (3)
      1. 1rlw picpic
        complexed with ca, cd; mutant
        1. chain a [23177] picpiclink
      2. 1cjy picpicxref
        complexed with ca, mes
        1. region a:13-141 [23178] picpiclink
        2. region b:1015-1141 [23179] picpiclink
      3. 1bci picpic
        complexed with ca
        1. chain a [23180] picpiclink
  3. Pten tumor suppressor (Phoshphoinositide phosphatase), C-terminal domain [49568]
    1. Human (Homo sapiens) [TaxId: 9606] [49569] (1)
      1. 1d5r picpicxref
        1. region a:188-351 [23181] picpiclink
  4. Phoshoinositide 3-kinase (PI3K) [49570]
    1. Pig (Sus scrofa) [TaxId: 9823] [49571] (5)
      1. 1e7u picpicxrefxrefxref
        complexed with kwt; mutant
        1. region a:351-524 [23182] picpiclink
      2. 1e8x picpicxrefxrefxref
        complexed with atp, lu; mutant
        1. region a:357-522 [23183] picpiclink
      3. 1e7v picpicxrefxrefxref
        complexed with ly2; mutant
        1. region a:354-524 [23184] picpiclink
      4. 1e90 picpicxrefxrefxref
        complexed with myc; mutant
        1. region a:357-521 [23185] picpiclink
      5. 1e8w picpicxrefxrefxref
        complexed with que; mutant
        1. region a:352-524 [23186] picpiclink
    2. Human (Homo sapiens) [TaxId: 9606] [49572] (3)
      1. 1e8y picpicxrefxrefxref
        mutant
        1. region a:357-522 [23187] picpiclink
      2. 1e8z picpicxrefxrefxref
        complexed with stu; mutant
        1. region a:357-522 [23188] picpiclink
      3. 1he8 picpicxrefxrefxrefxref
        complexed with gnp, mg; mutant
        1. region a:353-524 [23189] picpiclink
  5. Domain from protein kinase C delta [49573]
    rudiment form lacking calcium-binding site
    1. Rat (Rattus norvegicus) [TaxId: 10116] [49574] (1)
      1. 1bdy picpic
        mutant
        1. chain a [23190] picpiclink
        2. chain b [23191] picpiclink
  6. Domain from protein kinase C epsilon [69196]
    Calcium-independent
    1. Rat (Rattus rattus) [TaxId: 10117] [69197] (1)
      1. 1gmi picpic
        complexed with mg
        1. chain a [65309] picpiclink
  7. E3 ubiquitin-protein ligase Itchy [141103]
    1. Human (Homo sapiens) [TaxId: 9606] [141104] (1)
      SQ Q96J02 13-145
      1. 2nq3 picpic
        complexed with cl
        1. region a:13-145 [138452] picpiclink
  8. Unc-13 homolog A [141105]
    1. Rat (Rattus norvegicus) [TaxId: 10116] [141106] (6)
      SQ Q62768 1-128! SQ Q62768 2-150
      1. 2cjt picpic
        complexed with edo, fmt
        1. region a:1-128 [130549] picpiclink
      2. 2cjt picpic
        automatically matched to 2CJT A:1-128
        complexed with edo, fmt
        1. region b:1-128 [130550] picpiclink
      3. 2cjt picpic
        automatically matched to 2CJT A:1-128
        complexed with edo, fmt
        1. region c:2-128 [130551] picpiclink
      4. 2cjt picpic
        automatically matched to 2CJT A:1-128
        complexed with edo, fmt
        1. region d:2-128 [130552] picpiclink
      5. 2cjs picpic
        complexed with edo, gol, zn; mutant
        1. region a:2-150 [130547] picpiclink
      6. 2cjs picpic
        automatically matched to 2CJS A:2-150
        complexed with edo, gol, zn; mutant
        1. region b:2-150 [130548] picpiclink
  9. Multiple C2 and transmembrane domain-containing protein 2, MCTP2 [158940]
    1. Human (Homo sapiens) [TaxId: 9606] [158941] (1)
      SQ Q6DN12 504-629
      1. 2ep6 picpic
        3rd C2 domain
        1. region a:92-217 [146970] picpiclink
  10. Fantom [158942]
    RPGR-interacting protein 1-like protein
    1. Human (Homo sapiens) [TaxId: 9606] [158943] (1)
      SQ Q68CZ1 596-737
      1. 2yrb picpic
        1st C2 domain
        1. region a:596-737 [153741] picpiclink
  11. Phospholipase C-beta-2 [158944]
    1. Human (Homo sapiens) [TaxId: 9606] [158945] (2)
      SQ Q00722 678-799
      1. 2zkm picpicxrefxrefxref
        automatically matched to 2FJU B:678-799
        complexed with ca
        1. region x:678-799 [154588] picpiclink
      2. 2fju picpicxrefxrefxrefxref
        complexed with ca, gsp, mg
        1. region b:678-799 [145171] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk