Structural Classification of Proteins
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Superfamily: Glycosyl hydrolase domain

this domain is C-terminal to the catalytic beta/alpha barrel domain
link to SUPERFAMILY database - Superfamily

Lineage:

  1. Root: scop
  2. Class: All beta proteins [48724]
  3. Fold: Glycosyl hydrolase domain [51010]
    folded sheet; greek-key
  4. Superfamily: Glycosyl hydrolase domain [51011]
    this domain is C-terminal to the catalytic beta/alpha barrel domain
    link to SUPERFAMILY database - Superfamily

Families:

  1. alpha-Amylases, C-terminal beta-sheet domain [51012] (46)
    this domain follows the catalytic beta/alpha barrel domain
    1. Bacterial alpha-Amylase [51013]
      1. Bacillus licheniformis [TaxId: 1402] [51014] (8) picpic
      2. Pseudoalteromonas haloplanktis (Alteromonas haloplanktis) [TaxId: 228] [51015] (9) picpic
      3. Bacillus subtilis [TaxId: 1423] [51016] (2) picpic
        SQ P00691
      4. Bacillus stearothermophilus [TaxId: 1422] [51017] (1) picpic
      5. Bacillus sp., ksm-k38 [TaxId: 1409] [89382] (6) picpic
      6. Archaeon Pyrococcus woesei [TaxId: 2262] [89383] (3) picpic
      7. Bacillus sp. 707 [TaxId: 1416] [117297] (4) picpic
        SQ P19571 38-518
      8. Bacillus halmapalus [TaxId: 79882] [141551] (3) picpic
        SQ P19571 432-518
      9. Halothermothrix orenii [TaxId: 31909] [141552] (1) picpic
        SQ Q8GPL8 437-515
    2. Maltosyltransferase [63835]
      1. Thermotoga maritima [TaxId: 2336] [63836] (2) picpic
    3. Cyclodextrin glycosyltransferase [51018]
      contains two more all-beta domains in C-terminal region, Immunoglobulin-like and trasthyretin-like
      1. Bacillus circulans, different strains [TaxId: 1397] [51019] (36) picpic
      2. Bacillus stearothermophilus [TaxId: 1422] [51020] (1) picpic
      3. Bacillus stearothermophilus, maltogenic alpha-amylase [TaxId: 1422] [51021] (2) picpic
      4. Bacillus sp., strain 1011 [TaxId: 1409] [51022] (8) picpic
        SQ P05618
      5. Thermoanaerobacterium thermosulfurigenes, EM1 [TaxId: 33950] [51023] (2) picpic
      6. Thermoanaerobacterium [TaxId: 28895] [159261] (2) picpic
    4. Animal alpha-amylase [51024]
      1. Pig (Sus scrofa) [TaxId: 9823] [51025] (14) picpic
      2. Human (Homo sapiens) [TaxId: 9606] [51026] (43) picpic
        SQ P04746 16-511 ! SQ 04746
      3. Yellow mealworm (Tenebrio molitor), larva [TaxId: 7067] [51027] (4) picpic
    5. Fungal alpha-amylase [51028]
      1. Aspergillus niger, acid amylase [TaxId: 5061] [51029] (1) picpic
      2. Aspergillus oryzae, Taka-amylase [TaxId: 5062] [51030] (8) picpic
    6. Maltogenic amylase [51031]
      1. Thermus sp. [TaxId: 275] [51032] (2) picpic
      2. Bacillus sp., cyclomaltodextrinase [TaxId: 1409] [75016] (1) picpic
      3. Thermoactinomyces vulgaris, TVAI [TaxId: 2026] [75017] (9) picpic
      4. Thermoactinomyces vulgaris, TVAII [TaxId: 2026] [51033] (25) picpic
    7. Neopullulanase [82175]
      homologous to Maltogenic amylase
      1. Bacillus stearothermophilus [TaxId: 1422] [82176] (4) picpic
    8. Cyclomaltodextrinase [101917]
      protein shares similar domain organization with maltogenic amylases but differs in the spatial arrangement of its domains
      1. Flavobacterium sp. 92 [TaxId: 197856] [101918] (1) picpic
    9. Maltooligosyl trehalose synthase [82177]
      1. Archaeon Sulfolobus acidocaldarius [TaxId: 2285] [82178] (1) picpic
    10. Glycosyltrehalose trehalohydrolase [51034]
      1. Archaeon Sulfolobus solfataricus, km1 [TaxId: 2287] [51035] (2) picpic
      2. Deinococcus radiodurans [TaxId: 1299] [141553] (9) picpic
        SQ Q9RX51 529-600
    11. 1,4-alpha-glucan branching enzyme [82179]
      1. Escherichia coli [TaxId: 562] [82180] (1) picpic
    12. Isoamylase [51036]
      1. Pseudomonas amyloderamosa [TaxId: 32043] [51037] (1) picpic
    13. G4-amylase (1,4-alpha-D-glucan maltotetrahydrolase) [51038]
      single beta-sheet; probable result of a decay of the common-fold
      1. Pseudomonas stutzeri [TaxId: 316] [51039] (9) picpic
    14. Plant alpha-amylase [51040]
      single beta-sheet; probable result of a decay of the common-fold
      1. Barley (Hordeum vulgare), seeds, AMY2 isozyme [TaxId: 4513] [51041] (3) picpic
      2. Barley (Hordeum vulgare), AMY1 isozyme [TaxId: 4513] [89384] (10) picpic
    15. 4-alpha-glucanotransferase [75018]
      1. Thermotoga maritima [TaxId: 2336] [75019] (2) picpic
    16. Oligo-1,6-glucosidase [51042]
      1. Bacillus cereus [TaxId: 1396] [51043] (1) picpic
    17. Isomaltulose synthase PalI [89385]
      1. Klebsiella sp., lx3 [TaxId: 576] [89386] (1) picpic
    18. Amylosucrase [69328]
      1. Neisseria polysaccharea [TaxId: 489] [69329] (10) picpic
    19. Melibiase [75020]
      1. Chicken (Gallus gallus) [TaxId: 9031] [75021] (2) picpic
        alpha-N-acetylgalactosaminidase
      2. Rice (Oryza sativa) [TaxId: 4530] [89387] (1) picpic
        alpha-galactosidase
      3. Human (Homo sapiens) [TaxId: 9606] [101919] (2) picpic
        alpha-galactosidase A
      4. Trichoderma reesei [TaxId: 51453] [110300] (2) picpic
        SQ Q92456; Alpha-galactosidase agl1;
    20. A4 beta-galactosidase [82181]
      the catalytic domain of this protein is similar to that of the bacterial beta-amylase
      1. Thermus thermophilus [TaxId: 274] [82182] (2) picpic
    21. Sucrose phosphorylase [101920]
      single beta-sheet; probable result of a decay of the common-fold
      1. Bifidobacterium adolescentis [TaxId: 1680] [101921] (5) picpic
    22. Pullulanase PulA [159262]
      1. Klebsiella pneumoniae [TaxId: 573] [159263] (3) picpic
        SQ P07206 973-1090
  2. Composite domain of glycosyl hydrolase families 5, 30, 39 and 51 [89388] (6)
    interrupted by the catalytic domain; the C-terminal core is similar to the alpha-amylase domain
    1. Glucosylceramidase [89389]
      glycosyl hydrolase family 30; the N-terminal extension wraps around the C-terminal core
      1. Human (Homo sapiens) [TaxId: 9606] [89390] (27) picpic
    2. Glycosyl hydrolase family 5 xylanase [101922]
      1. Erwinia chrysanthemi [TaxId: 556] [101923] (1) picpic
    3. Alpha-l-arabinofuranosidase [101924]
      glycosyl hydrolase family 51
      1. Bacillus stearothermophilus [TaxId: 1422] [101925] (4) picpic
      2. Clostridium thermocellum [TaxId: 1515] [141554] (12) picpic
        SQ Q4CJG5 2-16,387-502
    4. Beta-D-xylosidase [101926]
      glycosyl hydrolase family 39
      1. Thermoanaerobacterium saccharolyticum [TaxId: 28896] [101927] (2) picpic
      2. Bacillus stearothermophilus [TaxId: 1422] [141555] (24) picpic
        SQ Q9ZFM2 5-14,362-503
  3. Putative alpha-L-fucosidase C-terminal domain [101928] (1)
    glycosyl hydrolase family 29; beta-sheet forms a closed beta-barrel (n=8, S=10)
    1. Putative alpha-L-fucosidase C-terminal domain [101929]
      1. Thermotoga maritima [TaxId: 2336] [101930] (3) picpic
        TM0306
  4. Putative glucosidase YicI, domain 3 [117298] (1)
    1. Putative glucosidase YicI, domain 3 [117299]
      1. Escherichia coli [TaxId: 562] [117300] (15) picpic
        SQ P31434
  5. Beta-galactosidase LacA, domain 2 [117301] (1)
    contains extra C-terminal beta-sandwich subdomain [greek-key; partial topological similarity to the immunoglobulin-like fold]
    1. Beta-galactosidase LacA, domain 2 [117302]
      1. Penicillium sp. [TaxId: 5081] [117303] (2) picpic
        SQ Q700S9 41-1011
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk