Structural Classification of Proteins
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Family: WD40-repeat

Lineage:

  1. Root: scop
  2. Class: All beta proteins [48724]
  3. Fold: 7-bladed beta-propeller [50964]
    consists of seven 4-stranded beta-sheet motifs; meander
  4. Superfamily: WD40 repeat-like [50978]
    also contains 8-bladed propellers
    link to SUPERFAMILY database - Superfamily
  5. Family: WD40-repeat [50979]

Protein Domains:

  1. beta1-subunit of the signal-transducing G protein heterotrimer [50980]
    1. Cow (Bos taurus) [TaxId: 9913] [50981] (11)
      1. 1tbg picpicxref
        1. chain a [27649] picpiclink
        2. chain b [27650] picpiclink
        3. chain c [27651] picpiclink
        4. chain d [27652] picpiclink
      2. 2trc picpicxrefxref
        complexed with gd
        1. chain b [27653] picpiclink
      3. 1a0r picpicxrefxref
        complexed with ace, far
        1. chain b [27658] picpiclink
      4. 1gg2 picpicxrefxrefxref
        complexed with gdp; mutant
        1. chain b [27655] picpiclink
      5. 1b9y picpicxrefxref
        complexed with gd
        1. chain a [27656] picpiclink
      6. 1gp2 picpicxrefxrefxref
        complexed with gdp; mutant
        1. chain b [27654] picpiclink
      7. 1omw picpicxrefxrefxrefxref
        complexed with cmt; mutant
        1. chain b [87089] picpiclink
      8. 1b9x picpicxrefxref
        complexed with gd; mutant
        1. chain a [27657] picpiclink
      9. 1xhm picpicxref
        automatically matched to d1tbga_
        1. region a:2-340 [122005] picpiclink
      10. 2bcj picpicxrefxrefxrefxrefxrefxref
        automatically matched to d1tbga_
        complexed with ace, alf, gdp, mg; mutant
        1. region b:2-340 [128289] picpiclink
      11. 1got picpicxrefxrefxref
        complexed with gdp
        1. chain b [27648] picpiclink
    2. Homo sapiens [TaxId: 9606] [159256] (1)
      1. 2qns picpicxref
        automatically matched to d1tbga_
        complexed with so4
        1. region a:7-340 [150953] picpiclink
  2. Tup1, C-terminal domain [50983]
    1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [50984] (1)
      1. 1erj picpic
        1. chain a [27660] picpiclink
        2. chain b [27661] picpiclink
        3. chain c [27662] picpiclink
  3. Groucho/tle1, C-terminal domain [75009]
    1. Human (Homo sapiens) [TaxId: 9606] [75010] (9)
      1. 1gxr picpic
        complexed with ca
        1. chain a [70722] picpiclink
        2. chain b [70723] picpiclink
      2. 2ce8 picpic
        automatically matched to d1gxra_
        1. region a:434-770 [130324] picpiclink
      3. 2ce8 picpic
        automatically matched to d1gxra_
        1. region b:434-770 [130325] picpiclink
      4. 2ce8 picpic
        automatically matched to d1gxra_
        1. region c:434-770 [130326] picpiclink
      5. 2ce8 picpic
        automatically matched to d1gxra_
        1. region d:434-770 [130327] picpiclink
      6. 2ce9 picpic
        automatically matched to d1gxra_
        1. region a:434-770 [130328] picpiclink
      7. 2ce9 picpic
        automatically matched to d1gxra_
        1. region b:434-770 [130329] picpiclink
      8. 2ce9 picpic
        automatically matched to d1gxra_
        1. region c:434-770 [130330] picpiclink
      9. 2ce9 picpic
        automatically matched to d1gxra_
        1. region d:434-770 [130331] picpiclink
  4. Arp2/3 complex 41 kDa subunit ARPC1 [69313]
    1. Cow (Bos taurus) [TaxId: 9913] [69314] (10)
      SQ Q58CQ2
      1. 1k8k picpicxrefxrefxrefxrefxrefxref
        1. chain c [68308] picpiclink
      2. 2p9i picpicxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1tyqc_
        complexed with adp, ca
        1. region c:2-372 [139584] picpiclink
      3. 1u2v picpicxrefxrefxrefxrefxrefxref
        complexed with adp, ca
        1. chain c [112991] picpiclink
      4. 2p9k picpicxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1tyqc_
        complexed with atp, ca
        1. region c:2-372 [139592] picpiclink
      5. 1tyq picpicxrefxrefxrefxrefxrefxref
        complexed with atp, ca
        1. chain c [112844] picpiclink
      6. 2p9l picpicxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1tyqc_
        1. region c:2-372 [139600] picpiclink
      7. 2p9s picpicxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1tyqc_
        complexed with atp, mg
        1. region c:2-372 [139624] picpiclink
      8. 2p9u picpicxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1tyqc_
        complexed with anp, ca
        1. region c:2-372 [139632] picpiclink
      9. 2p9n picpicxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1tyqc_
        complexed with adp, ca
        1. region c:2-372 [139608] picpiclink
      10. 2p9p picpicxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1tyqc_
        complexed with adp, ca
        1. region c:2-372 [139616] picpiclink
  5. Cdc4 propeller domain [82169]
    8-bladed beta-propeller without perfect 8-fold symmetry
    1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [82170] (1)
      1. 1nex picpicxrefxrefxref
        complexed with mse, tpo; mutant
        1. region b:370-744 [80444] picpiclink
        2. region d:370-744 [80448] picpiclink
  6. F-box/WD-repeat protein 1 (beta-TRCP1) [89376]
    1. Human (Homo sapiens) [TaxId: 9606] [89377] (1)
      1. 1p22 picpicxrefxrefxref
        complexed with sep
        1. region a:253-545 [87716] picpiclink
  7. Actin interacting protein 1 [89378]
    14 repeats are arranged into two seven-bladed beta-propeller domains swapped with the N-terminal strands
    1. Nematode (Caenorhabditis elegans) [TaxId: 6239] [89379] (2)
      1. 1nr0 picpic
        complexed with mn
        1. region a:2-312 [86078] picpiclink
        2. region a:313-611 [86079] picpiclink
      2. 1pev picpic
        1. region a:2-312 [88047] picpiclink
        2. region a:313-611 [88048] picpiclink
    2. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [89380] (2)
      1. 1pgu picpic
        complexed with mse, zn; mutant
        1. region a:2-326 [88069] picpiclink
        2. region a:327-613 [88070] picpiclink
        3. region b:2-326 [88071] picpiclink
        4. region b:327-615 [88072] picpiclink
      2. 1pi6 picpic
        complexed with zn; mutant
        1. region a:2-326 [88115] picpiclink
        2. region a:327-613 [88116] picpiclink
  8. Antiviral protein Ski8 (Ski8p) [110287]
    1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [110288] (2)
      SQ Q02793
      1. 1sq9 picpic
        complexed with so4
        1. chain a [105889] picpiclink
      2. 1s4u picpic
        1. chain x [112027] picpiclink
  9. Platelet-activating factor acetylhydrolase IB subunit alpha [159257]
    1. Mouse (Mus musculus) [TaxId: 10090] [159258] (10)
      SQ P43034 91-407
      1. 1vyh picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        1. region c:92-408 [144534] picpiclink
      2. 1vyh picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to 1VYH C:92-408
        1. region d:92-408 [144535] picpiclink
      3. 1vyh picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to 1VYH C:92-408
        1. region g:92-408 [144536] picpiclink
      4. 1vyh picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to 1VYH C:92-408
        1. region h:92-408 [144537] picpiclink
      5. 1vyh picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to 1VYH C:92-408
        1. region k:92-408 [144538] picpiclink
      6. 1vyh picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to 1VYH C:92-408
        1. region l:92-408 [144539] picpiclink
      7. 1vyh picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to 1VYH C:92-408
        1. region o:92-408 [144540] picpiclink
      8. 1vyh picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to 1VYH C:92-408
        1. region p:92-408 [144541] picpiclink
      9. 1vyh picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to 1VYH C:92-408
        1. region s:92-408 [144542] picpiclink
      10. 1vyh picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to 1VYH C:92-408
        1. region t:92-408 [144543] picpiclink
  10. F-box/WD repeat-containing protein 7, FBXW7 [159259]
    1. Human (Homo sapiens) [TaxId: 9606] [159260] (3)
      SQ Q969H0 365-706
      1. 2ovr picpicxrefxrefxref
        automatically matched to 2OVP B:2365-2706
        complexed with so4
        1. region b:2365-2706 [145736] picpiclink
      2. 2ovq picpicxrefxrefxref
        automatically matched to 2OVP B:2365-2706
        complexed with so4
        1. region b:2365-2706 [145734] picpiclink
      3. 2ovp picpicxrefxrefxref
        1. region b:2365-2706 [145732] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk